MUC12 Antibody (YA4570)
(Synonyms: MUC11; MUC-11; )
Based on 1 Customer Validation
MUC12 Antibody (YA4570) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to MUC12.
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Host:
Mouse
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Isotype:
IgG2b
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Application:
ICC/IF, FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|
| Dilution Ratio | 1:50-1:200 | 1:200-1:400 | 1:10000 |
Product Details
MUC12 Antibody (YA4570) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to MUC12.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 55.8 kDa
Purified recombinant fragment of human MUC12 (AA: extra 371-592) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG2b
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS with 0.05% sodium azide
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
MUC12 is involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF-beta in intestinal epithelium
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Subcellular Localization
Membrane; Single-pass type I membrane protein
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Expression
Tissue_specificity:It is widely distributed and highly expressed in the colon. Its expression is downregulated in the colon of patients with colorectal cancer, ulcerative colitis (UC) , and Crohn's disease (CD) .
Induction:By listeriolysin O -
Isoforms & Post-Translational Modification
Q9UKN1 has 2 isomers: Q9UKN1-1: 558164 Da (predicted); Q9UKN1-2: 542703 Da (predicted).
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SwissProt ID
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Synonyms
MUC11; MUC-11;
Documentation
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