CSPG5 - chondroitin sulfate proteoglycan 5 Gene

Also Known as NGC

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10675

About CSPG5

Cytogenetic location: 3p21.31 Genomic coordinates (GRCh38): 3:47,562,238-47,580,240 (from NCBI)

This gene has 5 transcripts (splice variants) and 241 orthologues. Restricted expression toward brain (RPKM 49.7).

Summary

The protein encoded by this gene is a proteoglycan that may function as a neural growth and differentiation factor. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]

CSPG5 Products (5)

mRNA Protein Name
NM_001206942.2 NP_001193871.1 chondroitin sulfate proteoglycan 5 isoform 2
NM_001206943.2 NP_001193872.1 chondroitin sulfate proteoglycan 5 isoform 3 precursor
NM_001206944.2 NP_001193873.1 chondroitin sulfate proteoglycan 5 isoform 4 precursor
NM_001206945.2 NP_001193874.1 chondroitin sulfate proteoglycan 5 isoform 5
NM_006574.4 NP_006565.2 chondroitin sulfate proteoglycan 5 isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12885772 GOA
Cellular Component GO Annotation Evidence References Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
12885772 GOA
located in Golgi-associated vesicle membrane IDA
IDA: Inferred from direct assay
12885772 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CSPG5 Protein Structure

Chon_Sulph_att

Chon_Sulph_att: Chondroitin sulphate attachment domain (31 - 277)

Neural_ProG_Cyt

Neural_ProG_Cyt: Neural chondroitin sulphate proteoglycan cytoplasmic domain (447 - 566)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 566 a.a.
Protein Preferred Names Protein Names

chondroitin sulfate proteoglycan 5

  • acidic leucine-rich EGF-like domain-containing brain protein

CSPG5 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
CSPG5 O95196 Gopc Mus musculus Q8BH60
Anti Tag CoIP
12885772
Cross
CSPG5 O95196 Gopc Mus musculus Q8BH60
Y2H
12885772
Cross
CSPG5 O95196 Gopc Mus musculus Q8BH60
Pull Down
12885772
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CSPG5 Proteins

Cat. No. Product Name Accession Purity
HY-P77833 CSPG5 Protein, Human (HEK293, His) O95196-1 (V31-C423) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03255 CSPG5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18656 Cspg5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25142 Cspg5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta CSPG5 VGNC VGNC:71526
Rattus norvegicus CSPG5 RGD RGD:2431
Bos taurus CSPG5 VGNC VGNC:27770
Felis catus CSPG5 VGNC VGNC:61228
Canis familiaris CSPG5 VGNC VGNC:39671
Mus musculus CSPG5 MGD MGI:1352747
Others CSPG5 NCBI