Cdc42bpb - CDC42 binding protein kinase beta Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 113960

Summary

Enables protein serine/threonine kinase activity and small GTPase binding activity. Involved in actomyosin structure organization; cell migration; and protein phosphorylation. Located in actomyosin. Orthologous to human CDC42BPB (CDC42 binding protein kinase beta). [provided by Alliance of Genome Resources, Apr 2022]

Cdc42bpb Products (1)

mRNA Protein Name
NM_053620.3 NP_446072.2 serine/threonine-protein kinase MRCK beta

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18854160 RGD
enables protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
9418861 RGD
enables small GTPase binding IDA
IDA: Inferred from direct assay
9418861 RGD
Biological Process GO Annotation Evidence References Source
involved in actin cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
9418861 RGD
involved in actomyosin structure organization IMP
IMP: Inferred from mutant phenotype
18854160 RGD
involved in cell migration IMP
IMP: Inferred from mutant phenotype
18854160 RGD
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
9418861 RGD
Cellular Component GO Annotation Evidence References Source
located in actomyosin IDA
IDA: Inferred from direct assay
18854160 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein kinase MRCK beta

  • CDC42 binding protein kinase beta (DMPK-like)

  • Cdc42-binding protein kinase beta

  • DMPK-like beta

  • MRCK beta

  • myotonic dystrophy kinase-related CDC42-binding kinase beta

  • myotonic dystrophy protein kinase-like beta

Cdc42bpb Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Cdc42bpb Q7TT49 Lurap1 Rattus norvegicus D4A8G3
Anti Bait CoIP
18854160
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02302 CDC42BPB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdc42bpb NCBI NCBI:9578