Clasp2 - cytoplasmic linker associated protein 2 Gene

Rattus norvegicus

Gene ID: 114514 | Gene type: protein coding

About Clasp2

Summary

Enables microtubule binding activity. Involved in cellular response to Insulin stimulus; negative regulation of microtubule depolymerization; and positive regulation of protein localization to membrane. Located in microtubule and ruffle membrane. Orthologous to human CLASP2 (cytoplasmic linker associated protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Clasp2 Products(1)

mRNA	Protein	Name
NM_053722.2	NP_446174.1	CLIP-associating protein 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables microtubule binding	IDA IDA: Inferred from direct assay	11290329	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to insulin stimulus	IEP IEP: Inferred from expression pattern	22992739	RGD
involved in negative regulation of microtubule depolymerization	IDA IDA: Inferred from direct assay	11290329	RGD
involved in positive regulation of protein localization to membrane	IMP IMP: Inferred from mutant phenotype	22992739	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in microtubule	IDA IDA: Inferred from direct assay	11290329	RGD
located in ruffle membrane	IDA IDA: Inferred from direct assay	22992739	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

CLIP-associating protein 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P0227	SHU 9119		99.83%	Unkown
HY-P1208	PG-931	Agonist	99.81%	Unkown
HY-RS02745	CLASP2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Clasp2	NCBI	NCBI:23122

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