Bcl2l10 - Bcl2-like 10 Gene
Species: Rattus norvegicus
About Bcl2l10
This gene has 1 transcript (splice variant), 132 orthologues, 13 paralogues and is associated with 7 phenotypes. Biased expression in Brain (RPKM 8.8), Adrenal (RPKM 4.9) and 7 other tissues.
Summary
Predicted to enable Caspase binding activity; protein heterodimerization activity; and protein homodimerization activity. Involved in oligodendrocyte differentiation. Predicted to be located in several cellular components, including cytosol; mitochondria-associated endoplasmic reticulum membrane; and mitochondrion. Predicted to be active in mitochondrial outer membrane. Human ortholog(s) of this gene implicated in multiple myeloma; myelodysplastic syndrome; and stomach carcinoma. Orthologous to human BCL2L10 (BCL2 like 10). [provided by Alliance of Genome Resources, Apr 2022]
Bcl2l10 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_053733.1 | NP_446185.1 | bcl-2-like protein 10 |
| NM_053733.1 | NP_446185.1 | bcl-2-like protein 10 |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in oligodendrocyte differentiation |
IEP
IEP: Inferred from expression pattern
|
12787069 | RGD |
Bcl2l10 Protein Structure
Bcl-2_like: cd06845 (5 - 150)
- 0
- 100
- 185 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
bcl-2-like protein 10 |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-150540 | Bcl-2-IN-10 | / | Unkown | |
| HY-RS01424 | BCL2L10 Human Pre-designed siRNA Set A | / | Unkown | |
| HY-RS01425 | Bcl2l10 Mouse Pre-designed siRNA Set A | / | Unkown | |
| HY-RS01426 | Bcl2l10 Rat Pre-designed siRNA Set A | / | Unkown |
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