Adam7 - a disintegrin and metallopeptidase domain 7 Gene

Mus musculus

Also known as EAP1; EAPI; ADAM 7

Gene ID: 11500 | Gene type: protein coding

About Adam7

Summary

This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. This gene is specifically expressed in epididymis where the encoded protein is transferred to the sperm surface during epididymal transit. This gene is located adjacent to a related gene from the ADAM family of proteins on chromosome 14. [provided by RefSeq, Oct 2015]

Adam7 Products(1)

mRNA	Protein	Name
NM_007402.2	NP_031428.2	disintegrin and metalloproteinase domain-containing protein 7 preproprotein

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables endopeptidase activity	IDA IDA: Inferred from direct assay	15574878	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	20945367	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in epididymis development	IMP IMP: Inferred from mutant phenotype	26246218	MGI
involved in epithelial cell morphogenesis	IMP IMP: Inferred from mutant phenotype	26246218	MGI
involved in positive regulation of flagellated sperm motility	IMP IMP: Inferred from mutant phenotype	26246218	MGI
involved in positive regulation of sperm capacitation	IMP IMP: Inferred from mutant phenotype	26246218	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in cell surface	IDA IDA: Inferred from direct assay	16407499	MGI
located in plasma membrane	IDA IDA: Inferred from direct assay	15883027	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

disintegrin and metalloproteinase domain-containing protein 7

a disintegrin and metalloprotease domain (ADAM) 7

epididymal apical protein I

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00285	ADAM7 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Adam7	NCBI	NCBI:8756

Name
Email *

	Sorry, but the email address you supplied was invalid.