Adam7 - a disintegrin and metallopeptidase domain 7 Gene

Also Known as EAP1; EAPI; ADAM 7

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11500

Summary

This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. This gene is specifically expressed in epididymis where the encoded protein is transferred to the sperm surface during epididymal transit. This gene is located adjacent to a related gene from the ADAM family of proteins on chromosome 14. [provided by RefSeq, Oct 2015]

Adam7 Products (1)

mRNA Protein Name
NM_007402.2 NP_031428.2 disintegrin and metalloproteinase domain-containing protein 7 preproprotein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables endopeptidase activity IDA
IDA: Inferred from direct assay
15574878 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
20945367 MGI
Biological Process GO Annotation Evidence References Source
involved in epididymis development IMP
IMP: Inferred from mutant phenotype
26246218 MGI
involved in epithelial cell morphogenesis IMP
IMP: Inferred from mutant phenotype
26246218 MGI
involved in positive regulation of flagellated sperm motility IMP
IMP: Inferred from mutant phenotype
26246218 MGI
involved in positive regulation of sperm capacitation IMP
IMP: Inferred from mutant phenotype
26246218 MGI
Cellular Component GO Annotation Evidence References Source
is active in cell surface IDA
IDA: Inferred from direct assay
16407499 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
15883027 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

disintegrin and metalloproteinase domain-containing protein 7

  • a disintegrin and metalloprotease domain (ADAM) 7

  • epididymal apical protein I

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00285 ADAM7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adam7 NCBI NCBI:8756