Adra2b - adrenergic receptor, alpha 2b Gene

Also known as [a]2B; a2b-AR; Adra-2b; alpha2B; alpha2-C2

About Adra2b

Summary

Enables alpha2-adrenergic receptor activity. Acts upstream of or within G protein-coupled receptor signaling pathway; MAPK cascade; and angiogenesis. Predicted to be located in cell surface; cytosol; and intracellular membrane-bounded organelle. Predicted to be integral component of plasma membrane. Is expressed in several structures, including adrenal gland; central nervous system; liver; and retina. Human ortholog(s) of this gene implicated in diabetic neuropathy; hypertension; myocardial infarction; obesity; and type 2 diabetes mellitus. Orthologous to human ADRA2B (adrenoceptor alpha 2B). [provided by Alliance of Genome Resources, Apr 2022]