Synpo2 - synaptopodin 2 Gene

Also Known as Myo; 1110069I04Rik; 2310068J10Rik; 9530006G20Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 118449

Summary

Enables 14-3-3 protein binding activity and muscle alpha-actinin binding activity. Predicted to be involved in several processes, including chaperone-mediated autophagy; positive regulation of actin filament bundle assembly; and regulation of Rho-dependent protein serine/threonine kinase activity. Located in nucleus. Is expressed in urinary system. Orthologous to human SYNPO2 (synaptopodin 2). [provided by Alliance of Genome Resources, Apr 2022]

Synpo2 Products (4)

mRNA Protein Name
NM_001388502.1 NP_001375431.1 synaptopodin-2 isoform 2
NM_001389265.1 NP_001376194.1 synaptopodin-2 isoform 3
NM_001389266.1 NP_001376195.1 synaptopodin-2 isoform 4
NM_080451.2 NP_536699.2 synaptopodin-2 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables 14-3-3 protein binding IDA
IDA: Inferred from direct assay
17923693 MGI
enables muscle alpha-actinin binding IDA
IDA: Inferred from direct assay
17923693 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15883195 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
17923693 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

synaptopodin-2

  • myopodin

  • mypodin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14098 SYNPO2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14099 SYNPO2L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Synpo2 NCBI NCBI:171024