Rhob - ras homolog family member B Gene

Also Known as Arh6; Arhb

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11852

Summary

Enables GDP binding activity. Involved in several processes, including negative regulation of cell cycle; positive regulation of angiogenesis; and positive regulation of apoptotic process. Acts upstream of or within intracellular protein transport. Located in endosome; nucleus; and plasma membrane. Is expressed in several structures, including branchial arch; embryo ectoderm; heart; nervous system; and otocyst. Orthologous to human RHOB (Ras homolog family member B). [provided by Alliance of Genome Resources, Apr 2022]

Rhob Products (1)

mRNA Protein Name
NM_007483.3 NP_031509.1 rho-related GTP-binding protein RhoB

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GDP binding IDA
IDA: Inferred from direct assay
8939998 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
8543060 MGI
Biological Process GO Annotation Evidence References Source
involved in cell adhesion IDA
IDA: Inferred from direct assay
11564874 MGI
acts upstream of or within intracellular protein transport IMP
IMP: Inferred from mutant phenotype
17623777 MGI
involved in negative regulation of cell cycle IMP
IMP: Inferred from mutant phenotype
11564874 MGI
involved in positive regulation of angiogenesis IMP
IMP: Inferred from mutant phenotype
14597666 MGI
involved in positive regulation of apoptotic process IDA
IDA: Inferred from direct assay
11353846 MGI
involved in regulation of modification of postsynaptic structure IDA
IDA: Inferred from direct assay
20203211 MGI
involved in regulation of modification of postsynaptic structure IMP
IMP: Inferred from mutant phenotype
20203211 MGI
Cellular Component GO Annotation Evidence References Source
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
20203211 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: Inferred from mutant phenotype
20203211 MGI
located in early endosome IDA
IDA: Inferred from direct assay
17623777 MGI
located in late endosome IDA
IDA: Inferred from direct assay
17623777 MGI
located in membrane IDA
IDA: Inferred from direct assay
8939998 MGI
located in nucleus IDA
IDA: Inferred from direct assay
14597666 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
15093731 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rho-related GTP-binding protein RhoB

  • aplysia ras-related homolog B

  • ras homolog B

  • ras homolog gene family, member AB

  • ras homolog gene family, member B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11946 RHOB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-176902 NSC126188 / Unkown
HY-28099 VEC6 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rhob NCBI NCBI:388