Canx - calnexin Gene

Also Known as Cnx; D11Ertd153e; 1110069N15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12330

Summary

Predicted to enable Apolipoprotein binding activity; calcium ion binding activity; and ionotropic glutamate receptor binding activity. Involved in clathrin-dependent endocytosis and synaptic vesicle endocytosis. Located in endoplasmic reticulum quality control compartment and membrane. Is integral component of membrane. Is expressed in brain; genitourinary system; liver; and musculature. Orthologous to human CANX (calnexin). [provided by Alliance of Genome Resources, Apr 2022]

Canx Products (3)

mRNA Protein Name
NM_001110499.1 NP_001103969.1 calnexin precursor
NM_001110500.1 NP_001103970.1 calnexin precursor
NM_007597.3 NP_031623.1 calnexin precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
8798466 MGI
Biological Process GO Annotation Evidence References Source
involved in clathrin-dependent endocytosis IMP
IMP: Inferred from mutant phenotype
21747946 MGI
involved in synaptic vesicle endocytosis IDA
IDA: Inferred from direct assay
21747946 MGI
involved in synaptic vesicle endocytosis IMP
IMP: Inferred from mutant phenotype
21747946 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
9034150 MGI
located in endoplasmic reticulum quality control compartment IDA
IDA: Inferred from direct assay
11408579 MGI
located in membrane IDA
IDA: Inferred from direct assay
12927782 MGI
located in nuclear membrane IDA
IDA: Inferred from direct assay
28811369 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calnexin

Recombinant Canx Proteins

Cat. No. Product Name Accession Purity
HY-P75460 Calnexin Protein, Mouse (HEK293, His) P35564 (H21-P482) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01879 CANX Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18340 Canx Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24819 Canx Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Canx NCBI NCBI:821