CPO - carboxypeptidase O Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 130749

About CPO

Cytogenetic location: 2q33.3 Genomic coordinates (GRCh38): 2:206,939,518-206,969,474 (from NCBI)

This gene has 1 transcript (splice variant), 251 orthologues and 8 paralogues. Biased expression in small intestine (RPKM 9.1) and thyroid (RPKM 0.3).

Summary

This gene is a member of the metallocarboxypeptidase gene family. [provided by RefSeq, Jan 2011]

CPO Products (1)

mRNA Protein Name
NM_173077.3 NP_775100.1 carboxypeptidase O precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables metallocarboxypeptidase activity IDA
IDA: Inferred from direct assay
21921028 GOA
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
21921028 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CPO Protein Structure

Peptidase_M14

Peptidase_M14: Zinc carboxypeptidase (56 - 336)

  • 0
  • 100
  • 200
  • 300
  • 374 a.a.
Protein Preferred Names Protein Names

carboxypeptidase O

  • metallocarboxypeptidase C

Related Diseases

Diseases Alias
Harderoporphyria

  • HARPO
Coproporphyria, Hereditary

  • Hereditary Coproporphyria

  • Coproporphyria

  • Coproporphyrinogen Oxidase Deficiency

  • HCP

  • Cpo Deficiency

  • Cpox Deficiency

  • Cpx Deficiency

  • Hereditary Coproporphyria Porphyria

  • Cpro Deficiency

  • Coproporphyria Hereditary

  • Porphyria Hepatica Ii

  • Porphyria Hepatica Coproporphyria

  • Porphyria, Hereditary Coproporphyria

  • Harderoporphyria
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-B0815S Chlorpyrifos-d10 Inhibitor 99.49% Unkown
HY-P11677 CPO_Aβ17-21P / Unkown
HY-RS03111 CPO Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03112 CPOX Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-184296 CPO 4 Inhibitor / Unkown
HY-RS20261 Cpox Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25786 Cpo Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CPO VGNC VGNC:27666
Macaca mulatta CPO VGNC VGNC:104517
Rattus norvegicus CPO RGD RGD:1588771
Canis familiaris CPO VGNC VGNC:39569
Others CPO NCBI