Cyp26a1 - cytochrome P450, family 26, subfamily a, polypeptide 1 Gene

Also Known as RAH; Cyp26; P450RA; P450RAI

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13082

Summary

Enables retinoic acid 4-hydroxylase activity. Involved in retinoic acid catabolic process. Acts upstream of or within several processes, including anterior/posterior pattern specification; cellular response to retinoic acid; and neural crest cell development. Predicted to be located in endoplasmic reticulum and membrane. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; extraembryonic component; and sensory organ. Orthologous to human CYP26A1 (Cytochrome P450 family 26 subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022]

Cyp26a1 Products (1)

mRNA Protein Name
NM_007811.2 NP_031837.2 cytochrome P450 26A1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables retinoic acid 4-hydroxylase activity IDA
IDA: Inferred from direct assay
9250660 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within anterior/posterior pattern specification IGI
IGI: Inferred from genetic interaction
17067568 MGI
acts upstream of or within anterior/posterior pattern specification IMP
IMP: Inferred from mutant phenotype
17067568 MGI
involved in cellular response to retinoic acid IEP
IEP: Inferred from expression pattern
18816858 MGI
acts upstream of or within central nervous system development IGI
IGI: Inferred from genetic interaction
17067568 MGI
acts upstream of or within central nervous system development IMP
IMP: Inferred from mutant phenotype
17067568 MGI
acts upstream of or within neural crest cell development IGI
IGI: Inferred from genetic interaction
17067568 MGI
involved in retinoic acid catabolic process IDA
IDA: Inferred from direct assay
9250660 MGI
involved in retinoic acid metabolic process IDA
IDA: Inferred from direct assay
9250660 MGI
acts upstream of or within retinoic acid metabolic process IMP
IMP: Inferred from mutant phenotype
15531370 MGI
acts upstream of retinoic acid receptor signaling pathway IDA
IDA: Inferred from direct assay
9250660 MGI
acts upstream of or within retinoic acid receptor signaling pathway IGI
IGI: Inferred from genetic interaction
17067568 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytochrome P450 26A1

  • cytochrome P450, 26, retinoic acid A1

  • cytochrome P450RAI

  • retinoic acid 4-hydroxylase

  • retinoic acid hydrolase

  • retinoic acid-metabolizing cytochrome

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-14531 Talarozole Inhibitor 99.75% Phase 2

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-169863 DC360 Agonist / Unkown
HY-182728 CD564 Inhibitor / Unkown
HY-RS03447 CYP26A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03448 CYP26B1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03449 CYP26C1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cyp26a1 NCBI NCBI:1592