Igsf8 - immunoglobulin superfamily, member 8 Gene

Also Known as PGRL; EWI-2; KCT-4; ESTM34

Species: Mus musculus

Gene Type: protein coding
Gene ID: 140559

Summary

Acts upstream of or within regulation of cell motility. Located in axon and synapse. Is expressed in several structures, including branchial arch; cardiac muscle tissue; central nervous system; epithelium; and sensory organ. Orthologous to human IGSF8 (immunoglobulin superfamily member 8). [provided by Alliance of Genome Resources, Apr 2022]

Igsf8 Products (1)

mRNA Protein Name
NM_080419.2 NP_536344.1 immunoglobulin superfamily member 8 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11504738 MGI
Biological Process GO Annotation Evidence References Source
involved in modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
33057002 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
33057002 MGI
acts upstream of or within regulation of cell motility IGI
IGI: Inferred from genetic interaction
11673522 MGI
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
22687584 MGI
located in synapse IDA
IDA: Inferred from direct assay
22687584 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

immunoglobulin superfamily member 8

  • CD81 partner 3

  • PG regulatory-like protein

  • glu-Trp-Ile EWI motif-containing protein 2

  • keratinocyte-associated transmembrane protein 4

  • prostaglandin regulatory-like protein

Recombinant Igsf8 Proteins

Cat. No. Product Name Accession Purity
HY-P76984 CD316/IGSF8 Protein, Mouse (HEK293, Fc) Q8R366 (R26-T577) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P76985 CD316/IGSF8 Protein, Mouse (HEK293, His) Q8R366 (R26-T577) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06651 IGSF8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19693 Igsf8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26188 Igsf8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Igsf8 NCBI NCBI:93185