2. Gene
  3. Cacng4 - calcium voltage-gated channel auxiliary subunit gamma 4 Gene

Cacng4 - calcium voltage-gated channel auxiliary subunit gamma 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 140725 | Gene type: protein coding

About Cacng4

Summary

Enables ionotropic glutamate receptor binding activity. Involved in positive regulation of AMPA Receptor activity and response to cocaine. Located in cell body; cell surface; and postsynaptic density membrane. Part of AMPA glutamate receptor complex. Is active in glutamatergic synapse. Is integral component of postsynaptic density membrane. Orthologous to human CACNG4 (calcium voltage-gated channel auxiliary subunit gamma 4). [provided by Alliance of Genome Resources, Apr 2022]

Cacng4 Products(1)

mRNA Protein Name
NM_080692.2 NP_542423.1 voltage-dependent calcium channel gamma-4 subunit
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables ionotropic glutamate receptor binding IDA
IDA: Inferred from direct assay
12771129 RGD
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of AMPA receptor activity IDA
IDA: Inferred from direct assay
12771129 RGD
involved in regulation of AMPA receptor activity IDA
IDA: Inferred from direct assay
17880894 RGD
involved in response to cocaine IDA
IDA: Inferred from direct assay
21276808 RGD
Cellular Component GO Annotation Evidence Reference Source
part of AMPA glutamate receptor complex IDA
IDA: Inferred from direct assay
19265014 RGD
located in cell body IDA
IDA: Inferred from direct assay
23751177 RGD
located in cell surface IDA
IDA: Inferred from direct assay
21276808 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
12771129 RGD
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
12771129 RGD
located in postsynaptic density membrane IDA
IDA: Inferred from direct assay
21276808 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

voltage-dependent calcium channel gamma-4 subunit

TARP gamma-4

calcium channel, voltage-dependent, gamma subunit 4

neuronal voltage-gated calcium channel gamma-4 subunit

transmembrane AMPAR regulatory protein gamma-4

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01812 CACNG4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cacng4 NCBI NCBI:27092