Cacng7 - calcium voltage-gated channel auxiliary subunit gamma 7 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 140728

Summary

Predicted to enable Calcium Channel regulator activity and voltage-gated Calcium Channel activity. Involved in positive regulation of dendrite extension; regulation of AMPA Receptor activity; and regulation of mRNA stability. Located in cerebellar mossy fiber; early endosome; and neuronal cell body. Part of AMPA glutamate receptor complex. Is active in glutamatergic synapse. Is integral component of postsynaptic density membrane. Orthologous to human CACNG7 (calcium voltage-gated channel auxiliary subunit gamma 7). [provided by Alliance of Genome Resources, Apr 2022]

Cacng7 Products (1)

mRNA Protein Name
NM_080695.2 NP_542426.1 voltage-dependent calcium channel gamma-7 subunit

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in positive regulation of dendrite extension IMP
IMP: Inferred from mutant phenotype
21610096 RGD
involved in regulation of AMPA receptor activity IDA
IDA: Inferred from direct assay
18817736 RGD
involved in regulation of mRNA stability IMP
IMP: Inferred from mutant phenotype
18923037 RGD
Cellular Component GO Annotation Evidence References Source
part of AMPA glutamate receptor complex IDA
IDA: Inferred from direct assay
19265014 RGD
located in cerebellar mossy fiber IDA
IDA: Inferred from direct assay
23751177 RGD
located in early endosome IDA
IDA: Inferred from direct assay
21610096 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
17475805 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
17475805 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
21610096 RGD
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
17475805 RGD
is active in postsynaptic density membrane IMP
IMP: Inferred from mutant phenotype
17475805 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

voltage-dependent calcium channel gamma-7 subunit

  • TARP gamma-7

  • calcium channel, voltage-dependent, gamma subunit 7

  • neuronal voltage-gated calcium channel gamma-7 subunit

  • transmembrane AMPAR regulatory protein gamma-7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01814 CACNG7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cacng7 NCBI NCBI:59284