CACNG7 - calcium voltage-gated channel auxiliary subunit gamma 7 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 59284

About CACNG7

Cytogenetic location: 19q13.42 Genomic coordinates (GRCh38): 19:53,909,278-53,943,950 (from NCBI)

This gene has 4 transcripts (splice variants), 257 orthologues and 5 paralogues. Restricted expression toward brain (RPKM 18.0).

Summary

The protein encoded by this gene is a type II transmembrane AMPA Receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a Calcium Channel gamma subunit. [provided by RefSeq, Dec 2010]

CACNG7 Products (3)

mRNA Protein Name
NM_001384801.1 NP_001371730.1 voltage-dependent calcium channel gamma-7 subunit isoform 2
NM_001412134.1 NP_001399063.1 voltage-dependent calcium channel gamma-7 subunit isoform 3
NM_031896.5 NP_114102.2 voltage-dependent calcium channel gamma-7 subunit isoform 1

CACNG7 Protein Structure

PMP22_Claudin

PMP22_Claudin: PMP-22/EMP/MP20/Claudin family (11 - 195)

  • 0
  • 100
  • 200
  • 275 a.a.
Protein Preferred Names Protein Names

voltage-dependent calcium channel gamma-7 subunit

  • TARP gamma-7

CACNG7 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CACNG7 P62955 SPACA1 Homo sapiens Q9HBV2
Validated Y2H
32296183
Intra
CACNG7 P62955 SPACA1 Homo sapiens Q9HBV2
Y2H Prey Pooling
32296183
Intra
CACNG7 P62955 SPACA1 Homo sapiens Q9HBV2
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Spinocerebellar Ataxia 23

  • Spinocerebellar Ataxia Type 23

  • SCA23

  • Ataxia, Spinocerebellar, Type 23
Isolated Growth Hormone Deficiency, Type Ib

  • Isolated Growth Hormone Deficiency Type Ib

  • IGHD1B

  • Ighd Ib

  • Growth Hormone Deficiency, Isolated, Type Ib

  • Congenital Ighd Type Ib

  • Congenital Isolated Gh Deficiency Type Ib

  • Congenital Isolated Growth Hormone Deficiency Type Ib

  • Dwarfism Of Sindh

  • Pituitary Dwarfism I

  • Isolated Growth Hormone Deficiency Type 1b

  • Ighd 1b

  • Growth Hormone Deficiency, Isolated, 1b
Arrhythmogenic Right Ventricular Cardiomyopathy

  • Arrhythmogenic Right Ventricular Dysplasia

  • Arvc

  • Arvd

  • Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy

  • Arvc Cardiomyopathy

  • Arrhythmogenic Right Ventricular Cardiomyopathy-Dysplasia

  • Arvd/C

  • Right Ventricular Dysplasia, Arrhythmogenic

  • Ventricular Dysplasia, Right, Arrhythmogenic

  • Cardiomyopathy, Ventricular, Right, Arrhythmogenic

  • Dysplasia, Arrhythmogenic Right Ventricular
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01814 CACNG7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CACNG7 VGNC VGNC:26692
Mus musculus CACNG7 MGD MGI:1932374
Macaca mulatta CACNG7 VGNC VGNC:70484
Felis catus CACNG7 VGNC VGNC:60312
Rattus norvegicus CACNG7 RGD RGD:628807
Canis familiaris CACNG7 VGNC VGNC:53674
Others CACNG7 NCBI