Gas2 - growth arrest specific 2 Gene
Also Known as Gas-2
Species: Mus musculus
Gene Type: protein coding
Gene ID: 14453
Summary
Predicted to enable actin filament binding activity and cytoskeletal anchor activity. Acts upstream of or within several processes, including ovarian follicle development; ovulation; and regulation of Notch signaling pathway. Predicted to be located in cytoplasm; cytoskeleton; and membrane. Predicted to be active in actin filament. Is expressed in several structures, including central nervous system; embryo mesenchyme; genitourinary system; lens; and limb. Orthologous to human GAS2 (growth arrest specific 2). [provided by Alliance of Genome Resources, Apr 2022]
Gas2 Products (15)
| mRNA | Protein | Name |
|---|---|---|
| NM_001330607.2 | NP_001317536.1 | growth arrest-specific protein 2 isoform 1 |
| NM_001330608.2 | NP_001317537.1 | growth arrest-specific protein 2 isoform 2 |
| NM_001412458.1 | NP_001399387.1 | growth arrest-specific protein 2 isoform 1 |
| NM_001412459.1 | NP_001399388.1 | growth arrest-specific protein 2 isoform 1 |
| NM_001412460.1 | NP_001399389.1 | growth arrest-specific protein 2 isoform 1 |
| NM_001412461.1 | NP_001399390.1 | growth arrest-specific protein 2 isoform 1 |
| NM_001412462.1 | NP_001399391.1 | growth arrest-specific protein 2 isoform 1 |
| NM_001412463.1 | NP_001399392.1 | growth arrest-specific protein 2 isoform 1 |
| NM_001412464.1 | NP_001399393.1 | growth arrest-specific protein 2 isoform 1 |
| NM_001412465.1 | NP_001399394.1 | growth arrest-specific protein 2 isoform 1 |
| NM_001412466.1 | NP_001399395.1 | growth arrest-specific protein 2 isoform 3 |
| NM_001412467.1 | NP_001399396.1 | growth arrest-specific protein 2 isoform 3 |
| NM_001412468.1 | NP_001399397.1 | growth arrest-specific protein 2 isoform 3 |
| NM_001412469.1 | NP_001399398.1 | growth arrest-specific protein 2 isoform 3 |
| NM_008087.4 | NP_032113.1 | growth arrest-specific protein 2 isoform 1 |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within antral ovarian follicle growth |
IMP
IMP: Inferred from mutant phenotype
|
27734842 | MGI |
| acts upstream of or within basement membrane organization |
IMP
IMP: Inferred from mutant phenotype
|
27734842 | MGI |
| acts upstream of or within initiation of primordial ovarian follicle growth |
IMP
IMP: Inferred from mutant phenotype
|
27734842 | MGI |
| acts upstream of or within ovulation |
IMP
IMP: Inferred from mutant phenotype
|
27734842 | MGI |
| acts upstream of or within regulation of Notch signaling pathway |
IMP
IMP: Inferred from mutant phenotype
|
27734842 | MGI |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
growth arrest-specific protein 2 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(5)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-120679 | XK469 | Inhibitor | 98% | Unkown |
| HY-RS05282 | GAS2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS05283 | GAS2L1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS05284 | GAS2L3 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-175485 | GaSal-2 | Inhibitor | / | Unkown |
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service