2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. XK469

XK469 (NSC 697887) is a quinoxaline-based topoisomerase II inhibitor. XK469 exhibits antiproliferative activity against neuroblastoma cells. XK469 can be used in the research of neuroblastoma.

For research use only. We do not sell to patients.

XK469

XK469 Chemical Structure

CAS No. : 157435-10-4

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Based on 1 publication(s) in Google Scholar

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Description

XK469 (NSC 697887) is a quinoxaline-based topoisomerase II inhibitor. XK469 exhibits antiproliferative activity against neuroblastoma cells. XK469 can be used in the research of neuroblastoma[1].

IC50 & Target[1]

Topoisomerase II

 

In Vitro

XK469 (72 h) inhibits the proliferation of SK-N-SH and IMR-3 neuroblastoma cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

XK469 Related Antibodies

Cell Viability Assay[1]

Cell Line: SK-N-SH cells; IMR-32 cells
Concentration: /
Incubation Time: 72 h
Result: Had IC50 values of 4.6 μM and 13.0 μM for SK-N-SH and IMR-32.
Molecular Weight

344.75

Formula

C17H13ClN2O4
CAS No.
Appearance

Solid

SMILES

CC(C(O)=O)OC1=CC=C(C=C1)OC2=NC3=CC(Cl)=CC=C3N=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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XK469 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

XK469157435-10-4NSC 697887XK 469XK-469NSC697887NSC-697887TopoisomeraseGAS2 InhibitorInhibitorinhibitorinhibit

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