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Cat. No.: HY-120679

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XK469

Name: XK469
Brand: MedChemExpress
SKU: HY-120679
Price: 240.00 USD
Availability: PreOrder

(Synonyms: NSC 697887)

XK469 (NSC 697887) is a quinoxaline-based topoisomerase II inhibitor. XK469 exhibits antiproliferative activity against neuroblastoma cells. XK469 can be used in the research of neuroblastoma.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Pureté : 98%
CAS No.: 157435-10-4
Formule: C₁₇H₁₃ClN₂O₄
Masse moléculaire:344.75

Stockage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

XK469 Chemical Structure

CAS No.: 157435-10-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
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Description

XK469 (NSC 697887) is a quinoxaline-based topoisomerase II inhibitor. XK469 exhibits antiproliferative activity against neuroblastoma cells. XK469 can be used in the research of neuroblastoma^[1].

IC₅₀ & Target

^[1]

Topoisomerase II

Voir tous les produits spécifiques à Isoform Topoisomerase :

In Vitro

XK469 (72 h) inhibits the proliferation of SK-N-SH and IMR-3 neuroblastoma cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[1]

Cell Line:

SK-N-SH cells; IMR-32 cells
Concentration:

/
Incubation Time:

72 h
Result:

Had IC₅₀ values of 4.6 μM and 13.0 μM for SK-N-SH and IMR-32.

Related Protocols :

Cell Viability Determination by MTT Colorimetric Assay

Chemical Information

CAS No. 157435-10-4
Appearance Solid
Masse moléculaire 344.75
Formule C₁₇H₁₃ClN₂O₄
Color White to off-white
SMILES

CC(C(O)=O)OC1=CC=C(C=C1)OC2=NC3=CC(Cl)=CC=C3N=C2
Synonyms

NSC 697887
Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (272 KB)
SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Montana M, et al. Synthesis of new quinoxalines containing an oxirane ring by the TDAE strategy and in vitro evaluation in neuroblastoma cell lines. Molecules. 2014;19(9):14987-14998. Published 2014 Sep 18. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

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Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
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XK469

Voir tous les produits spécifiques à Isoform Topoisomerase

Activité biologique

Description

IC50 & Target

In Vitro

Chemical Information

Pureté et documentation

Références

Calculators

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XK469 Related Classifications

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