GSG1L - GSG1 like Gene

Also Known as PRO19651

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 146395

About GSG1L

Cytogenetic location: 16p12.1 Genomic coordinates (GRCh38): 16:27,787,528-28,063,714 (from NCBI)

This gene has 5 transcripts (splice variants), 232 orthologues and 10 paralogues. Biased expression in brain (RPKM 2.2), heart (RPKM 1.7) and 2 other tissues.

Summary

Predicted to be involved in regulation of AMPA Receptor activity. Predicted to be located in postsynaptic density. Predicted to be active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and plasma membrane. Predicted to be integral component of postsynaptic density membrane. [provided by Alliance of Genome Resources, Apr 2022]

GSG1L Products (4)

mRNA Protein Name
NM_001109763.2 NP_001103233.1 germ cell-specific gene 1-like protein isoform 1 precursor
NM_001323900.2 NP_001310829.1 germ cell-specific gene 1-like protein isoform 3 precursor
NM_001323901.2 NP_001310830.1 germ cell-specific gene 1-like protein isoform 4 precursor
NM_144675.3 NP_653276.1 germ cell-specific gene 1-like protein isoform 2

GSG1L Protein Structure

GSG-1

GSG-1: GSG1-like protein (2 - 133)

  • 0
  • 100
  • 200
  • 300
  • 331 a.a.
Protein Preferred Names Protein Names

germ cell-specific gene 1-like protein

  • GSG1-like protein

GSG1L Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
GSG1L Q6UXU4 LXN Homo sapiens Q9BS40
Y2H Prey Pooling
25416956
Intra
GSG1L Q6UXU4 LXN Homo sapiens Q9BS40
Validated Y2H
25416956
Intra
GSG1L Q6UXU4 LXN Homo sapiens Q9BS40
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Arthrogryposis, Distal, Type 2a

  • Freeman-Sheldon Syndrome

  • Craniocarpotarsal Dystrophy

  • Craniocarpotarsal Dysplasia

  • DA2A

  • Whistling Face-Windmill Vane Hand Syndrome

  • Fss

  • Distal Arthrogryposis Type 2a

  • Whistling Face Syndrome

  • Freeman-Burian Syndrome

  • Arthrogryposis Distal Type 2a

  • Distal Arthrogryposis, Type 2a

  • Fbs

  • Arthrogryposis, Distal, 2a
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05861 GSG1L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus GSG1L VGNC VGNC:80579
Bos taurus GSG1L VGNC VGNC:29677
Canis familiaris GSG1L VGNC VGNC:41529
Rattus norvegicus GSG1L RGD RGD:1562278
Macaca mulatta GSG1L VGNC VGNC:82152
Mus musculus GSG1L MGD MGI:2685483
Others GSG1L NCBI