Kpnb1 - karyopherin (importin) beta 1 Gene

Also Known as IPOB; Impnb

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16211

Summary

Enables HSP90 protein binding activity; importin-alpha family protein binding activity; and nuclear import signal receptor activity. Acts upstream of or within ribosomal protein import into nucleus. Located in cytoplasmic stress granule. Part of protein-containing complex. Is expressed in brain; gonad; liver; neural retina; and pancreas. Orthologous to human KPNB1 (karyopherin subunit beta 1). [provided by Alliance of Genome Resources, Apr 2022]

Kpnb1 Products (1)

mRNA Protein Name
NM_008379.3 NP_032405.3 importin subunit beta-1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables Hsp90 protein binding IDA
IDA: Inferred from direct assay
19581287 MGI
enables importin-alpha family protein binding IPI
IPI: Inferred from physical interaction
20699224 MGI
enables nuclear import signal receptor activity IDA
IDA: Inferred from direct assay
11809816 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10891500 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within protein import into nucleus IDA
IDA: Inferred from direct assay
15689618 MGI
acts upstream of or within ribosomal protein import into nucleus IDA
IDA: Inferred from direct assay
11809816 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasmic stress granule IDA
IDA: Inferred from direct assay
27430620 MGI
part of protein-containing complex IDA
IDA: Inferred from direct assay
19796622 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

importin subunit beta-1

  • PTAC97

  • SCG

  • importin beta

  • karyopherin subunit beta-1

  • nuclear factor p97

  • pore targeting complex 97 kDa subunit

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-170316 Ibetazol Inhibitor 99.80% Unkown
HY-RS07422 KPNB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18529 Kpnb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25011 Kpnb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kpnb1 NCBI NCBI:3837