Ucn2 - urocortin 2 Gene

Also Known as Ucn3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 170896

Summary

Enables corticotropin-releasing hormone receptor 2 binding activity. Involved in several processes, including cellular response to glucocorticoid stimulus; cellular response to hypoxia; and negative regulation of gonadotropin secretion. Located in extracellular space. Biomarker of colitis. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human UCN2 (urocortin 2). [provided by Alliance of Genome Resources, Apr 2022]

Ucn2 Products (1)

mRNA Protein Name
NM_133385.2 NP_596876.2 urocortin-2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables corticotropin-releasing hormone receptor 2 binding IPI
IPI: Inferred from physical interaction
19334530 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to glucocorticoid stimulus IEP
IEP: Inferred from expression pattern
17283244 RGD
involved in cellular response to hypoxia IEP
IEP: Inferred from expression pattern
14519439 RGD
involved in negative regulation of follicle-stimulating hormone secretion IMP
IMP: Inferred from mutant phenotype
19193717 RGD
involved in negative regulation of gene expression IMP
IMP: Inferred from mutant phenotype
19193717 RGD
involved in negative regulation of luteinizing hormone secretion IMP
IMP: Inferred from mutant phenotype
19193717 RGD
involved in response to immobilization stress IEP
IEP: Inferred from expression pattern
12869794 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
17283244 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

urocortin-2

  • ucn II

  • urocortin 3

  • urocortin II

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15408 UCN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15583 UTS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20833 Uts2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27347 Uts2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ucn2 NCBI NCBI:90226