2. Gene
  3. A1cf - APOBEC1 complementation factor Gene

A1cf - APOBEC1 complementation factor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Acf; A1cft; Apobec-1

Gene ID: 170912 | Gene type: protein coding

About A1cf

Summary

Enables mRNA binding activity. Involved in cytidine to uridine editing and positive regulation of protein secretion. Located in cytoplasm and heterochromatin. Part of mRNA editing complex. Human ortholog(s) of this gene implicated in gout. Orthologous to human A1CF (APOBEC1 complementation factor). [provided by Alliance of Genome Resources, Apr 2022]

A1cf Products(1)

mRNA Protein Name
NM_133400.1 NP_596891.1 APOBEC1 complementation factor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables mRNA binding IDA
IDA: Inferred from direct assay
11870221 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
10781591 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cytidine to uridine editing IMP
IMP: Inferred from mutant phenotype
10669759 RGD
involved in positive regulation of protein secretion IMP
IMP: Inferred from mutant phenotype
20541607 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11870221 RGD
located in heterochromatin IDA
IDA: Inferred from direct assay
11870221 RGD
part of mRNA editing complex IDA
IDA: Inferred from direct assay
16820530 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

APOBEC1 complementation factor

APOBEC1 complementation factort

APOBEC1-stimulating protein

Apobec-1 complementation factor, APOBEC-1 stimulating protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00009 A1CF Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22090 A1cf Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens A1cf NCBI NCBI:29974