Plcd1 - phospholipase C, delta 1 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18799

Summary

Enables Phospholipase C activity and phospholipid binding activity. Acts upstream of or within angiogenesis; labyrinthine layer blood vessel development; and regulation of cell population proliferation. Located in cytosol. Is expressed in several structures, including alimentary system; appendicular skeleton; cranium; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in nonsyndromic congenital nail disorder 3. Orthologous to human PLCD1 (Phospholipase C delta 1). [provided by Alliance of Genome Resources, Apr 2022]

Plcd1 Products (4)

mRNA Protein Name
NM_001293648.1 NP_001280577.1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform 1
NM_019676.3 NP_062650.1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform 2
NM_001293648.1 NP_001280577.1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform 1
NM_019676.3 NP_062650.1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23055941 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within angiogenesis IGI
IGI: Inferred from genetic interaction
16314520 MGI
acts upstream of or within labyrinthine layer blood vessel development IGI
IGI: Inferred from genetic interaction
16314520 MGI
acts upstream of or within regulation of cell population proliferation IGI
IGI: Inferred from genetic interaction
16314520 MGI
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
15899900 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1

  • PLC-delta 1

  • phosphoinositide phospholipase C-delta-1

  • phospholipase C delta 1 Lf

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10656 PLCD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plcd1 NCBI NCBI:5333