Pou2f1 - POU domain, class 2, transcription factor 1 Gene

Also Known as Oct1; Otf1; NF-A1; Oct-1; Otf-1; 2810482H01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18986

Summary

Enables chromatin binding activity and sequence-specific DNA binding activity. Acts upstream of or within lens induction in camera-type eye; olfactory placode formation; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including central nervous system; genitourinary system; lung; sensory organ; and tooth. Orthologous to human POU2F1 (POU class 2 homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Pou2f1 Products (5)

mRNA Protein Name
NM_001368808.1 NP_001355737.1 POU domain, class 2, transcription factor 1 isoform 1
NM_011137.3 NP_035267.2 POU domain, class 2, transcription factor 1 isoform A
NM_198932.3 NP_945150.2 POU domain, class 2, transcription factor 1 isoform Z
NM_198933.3 NP_945151.2 POU domain, class 2, transcription factor 1 isoform L
NM_198934.3 NP_945152.2 POU domain, class 2, transcription factor 1 isoform B

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
9738004 MGI
enables chromatin binding IDA
IDA: Inferred from direct assay
16735694 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16002402 MGI
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
1690859 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within lens induction in camera-type eye IGI
IGI: Inferred from genetic interaction
17140559 MGI
acts upstream of or within olfactory placode formation IGI
IGI: Inferred from genetic interaction
17140559 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
16002402 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
17140559 MGI
acts upstream of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
16002402 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
7969117 MGI
part of transcription regulator complex IDA
IDA: Inferred from direct assay
7969117 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

POU domain, class 2, transcription factor 1

  • octamer-binding protein 1

  • octamer-binding transcription factor 1

  • ubiquitous transcription factor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10897 POU2F1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174788 HHV-1 UL48 mRNA / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pou2f1 NCBI NCBI:5451