HHV-1 UL48 mRNA

HHV-1 UL48 mRNA encodes the UL48 protein of human herpesvirus 1 (HHV-1). UL48 is a tanscriptional activator of immediate-early (IE) gene products (alpha genes). It acts as a key activator of lytic infection by initiating the lytic program through the assembly of the transcriptional regulatory VP16-induced complex composed of VP16 and two cellular factors, HCFC1 and POU2F 1.

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