Pou3f1 - POU class 3 homeobox 1 Gene

Also Known as Otf6; Scip; Oct-6; Tst-1; Testes-1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 192110

Summary

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in glial cell differentiation and negative regulation of transcription by RNA polymerase II. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleus. Orthologous to human POU3F1 (POU class 3 homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Pou3f1 Products (1)

mRNA Protein Name
NM_138838.2 NP_620193.1 POU domain, class 3, transcription factor 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
9196379 RGD
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
9632656 RGD
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
1705013 RGD
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
1705013 RGD
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
9196379 RGD
Biological Process GO Annotation Evidence References Source
involved in glial cell differentiation IDA
IDA: Inferred from direct assay
1975954 RGD
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
1975954 RGD
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
1705013 RGD
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
9632656 RGD
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
9632656 RGD
involved in regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
9196379 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

POU domain, class 3, transcription factor 1

  • OTF-6

  • POU domain transcription factor SCIP

  • octamer-binding protein 6

  • octamer-binding transcription factor 6

  • octoamer transcription factor-6

  • octomer-6

  • suppressed cAMP-inducible POU

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10900 POU3F1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pou3f1 NCBI NCBI:5453