Atp5po - ATP synthase peripheral stalk subunit OSCP Gene

Also Known as Atpo; Oscp; Atp5o

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 192241

Summary

Enables estradiol binding activity. Contributes to ATP hydrolysis activity. Involved in ATP biosynthetic process; cellular response to cAMP; and cellular response to cytokine stimulus. Located in cell surface; mitochondrion; and plasma membrane. Part of mitochondrial proton-transporting ATP Synthase complex, coupling factor F(o). Biomarker of hypothyroidism. Orthologous to human ATP5PO (ATP Synthase peripheral stalk subunit OSCP). [provided by Alliance of Genome Resources, Apr 2022]

Atp5po Products (1)

mRNA Protein Name
NM_138883.1 NP_620238.1 ATP synthase subunit O, mitochondrial precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
contributes to ATP hydrolysis activity IDA
IDA: Inferred from direct assay
9753477 RGD
enables estradiol binding IDA
IDA: Inferred from direct assay
10215039 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
9753477 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to cAMP IEP
IEP: Inferred from expression pattern
26775111 RGD
involved in cellular response to cytokine stimulus IEP
IEP: Inferred from expression pattern
24692845 RGD
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
26223201 RGD
part of proton-transporting ATP synthase complex IDA
IDA: Inferred from direct assay
17575325 RGD
part of proton-transporting ATP synthase complex, coupling factor F(o) IDA
IDA: Inferred from direct assay
10887193 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ATP synthase subunit O, mitochondrial

  • ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein)

  • oligomycin sensitivity conferral protein

  • sperm flagella protein 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01213 ATP5PO Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atp5po NCBI NCBI:539