Ptprt - protein tyrosine phosphatase, receptor type, T Gene

Also Known as R-PTP-T; RPTPrho; RPTP-rfo; RPTP-rho; RPTPmam4; mRPTPrho; mKIAA0283

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19281

Summary

Enables several functions, including alpha-catenin binding activity; beta-catenin binding activity; and delta-catenin binding activity. Acts upstream of or within protein dephosphorylation. Predicted to be located in cell surface and plasma membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; nervous system; respiratory system; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in colorectal Cancer and esophagus squamous cell carcinoma. Orthologous to human PTPRT (protein tyrosine Phosphatase receptor type T). [provided by Alliance of Genome Resources, Apr 2022]

Ptprt Products (4)

mRNA Protein Name
NM_001291149.1 NP_001278078.1 receptor-type tyrosine-protein phosphatase T isoform a precursor
NM_001291150.1 NP_001278079.1 receptor-type tyrosine-protein phosphatase T isoform b precursor
NM_001291151.1 NP_001278080.1 receptor-type tyrosine-protein phosphatase T isoform c precursor
NM_021464.5 NP_067439.1 receptor-type tyrosine-protein phosphatase T isoform d precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables alpha-actinin binding IDA
IDA: Inferred from direct assay
16973135 MGI
enables alpha-catenin binding IDA
IDA: Inferred from direct assay
16973135 MGI
enables beta-catenin binding IDA
IDA: Inferred from direct assay
16973135 MGI
enables cadherin binding IPI
IPI: Inferred from physical interaction
16973135 MGI
enables delta-catenin binding IPI
IPI: Inferred from physical interaction
16973135 MGI
enables gamma-catenin binding IPI
IPI: Inferred from physical interaction
16973135 MGI
enables protein tyrosine phosphatase activity IMP
IMP: Inferred from mutant phenotype
16973135 MGI
enables thiolester hydrolase activity IDA
IDA: Inferred from direct assay
16973135 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within protein dephosphorylation IDA
IDA: Inferred from direct assay
16973135 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

receptor-type tyrosine-protein phosphatase T

  • receptor protein tyrosine phosphatase-rho

  • receptor-type tyrosine-protein phosphatase rho

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-183573 PTPRO-IN-1 Inhibitor / Unkown
HY-RS11450 PTPRT Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptprt NCBI NCBI:11122