2. Gene
  3. Rasgrf2 - RAS protein-specific guanine nucleotide-releasing factor 2 Gene

Rasgrf2 - RAS protein-specific guanine nucleotide-releasing factor 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Grf2; Ras-GRF2; 6330417G04Rik

Gene ID: 19418 | Gene type: protein coding

About Rasgrf2

Summary

Predicted to enable guanyl-nucleotide exchange factor activity. Acts upstream of or within long-term synaptic potentiation and regulation of NMDA Receptor activity. Predicted to be located in endoplasmic reticulum. Is expressed in brain; hypothalamus mantle layer; medulla oblongata basal plate mantle layer; and pons mantle layer. Orthologous to human RASGRF2 (Ras protein specific guanine nucleotide releasing factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Rasgrf2 Products(1)

mRNA Protein Name
NM_009027.4 NP_033053.2 ras-specific guanine nucleotide-releasing factor 2
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within long-term synaptic potentiation IGI
IGI: Inferred from genetic interaction
20661302 MGI
involved in postsynaptic modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
23940355 MGI
involved in postsynaptic modulation of chemical synaptic transmission IEP
IEP: Inferred from expression pattern
23940355 MGI
involved in postsynaptic modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
23940355 MGI
acts upstream of or within regulation of NMDA receptor activity IGI
IGI: Inferred from genetic interaction
15029245 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
23940355 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
23940355 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
23940355 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-specific guanine nucleotide-releasing factor 2

ras guanine nucleotide exchange factor 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11692 RASGRF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rasgrf2 NCBI NCBI:5924