Rasgrf2 - RAS protein-specific guanine nucleotide-releasing factor 2 Gene

Also Known as Grf2; Ras-GRF2; 6330417G04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19418

Summary

Predicted to enable guanyl-nucleotide exchange factor activity. Acts upstream of or within long-term synaptic potentiation and regulation of NMDA Receptor activity. Predicted to be located in endoplasmic reticulum. Is expressed in brain; hypothalamus mantle layer; medulla oblongata basal plate mantle layer; and pons mantle layer. Orthologous to human RASGRF2 (Ras protein specific guanine nucleotide releasing factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Rasgrf2 Products (1)

mRNA Protein Name
NM_009027.4 NP_033053.2 ras-specific guanine nucleotide-releasing factor 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within long-term synaptic potentiation IGI
IGI: Inferred from genetic interaction
20661302 MGI
involved in postsynaptic modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
23940355 MGI
involved in postsynaptic modulation of chemical synaptic transmission IEP
IEP: Inferred from expression pattern
23940355 MGI
involved in postsynaptic modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
23940355 MGI
acts upstream of or within regulation of NMDA receptor activity IGI
IGI: Inferred from genetic interaction
15029245 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
23940355 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
23940355 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
23940355 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-specific guanine nucleotide-releasing factor 2

  • ras guanine nucleotide exchange factor 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11692 RASGRF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rasgrf2 NCBI NCBI:5924