Pld6 - phospholipase D family, member 6 Gene

Mus musculus

Also known as Zuc; Gm10; mZuc; mitoPLD; 4933433K01Rik

Gene ID: 194908 | Gene type: protein coding

About Pld6

Summary

Enables identical protein binding activity. Involved in gamete generation; meiotic cell cycle; and piRNA metabolic process. Located in mitochondrial outer membrane. Orthologous to human PLD6 (Phospholipase D family member 6). [provided by Alliance of Genome Resources, Apr 2022]

Pld6 Products(2)

mRNA	Protein	Name
NM_001290283.1	NP_001277212.1	mitochondrial cardiolipin hydrolase isoform a
NM_183139.2	NP_898962.2	mitochondrial cardiolipin hydrolase isoform b

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	23064227	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	25762440	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in P granule organization	IMP IMP: Inferred from mutant phenotype	21397848	MGI
involved in meiotic cell cycle	IMP IMP: Inferred from mutant phenotype	21397847	MGI
involved in piRNA processing	IMP IMP: Inferred from mutant phenotype	21397848	MGI
involved in spermatid development	IMP IMP: Inferred from mutant phenotype	21397847	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in mitochondrial outer membrane	IDA IDA: Inferred from direct assay	21397847	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

mitochondrial cardiolipin hydrolase

choline phosphatase 6	mitochondrial phospholipase
novel Phospholipase D Active site motif-containing protein	phosphatidylcholine-hydrolyzing phospholipase D6
phospholipase D6	protein zucchini homolog

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10675	PLD6 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pld6	NCBI	NCBI:201164

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