2. Gene
  3. Rbl1 - RB transcriptional corepressor like 1 Gene

Rbl1 - RB transcriptional corepressor like 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as PRB1; p107

Gene ID: 19650 | Gene type: protein coding

About Rbl1

Summary

Predicted to enable RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and promoter-specific chromatin binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including genitourinary system; hemolymphoid system gland; limb; liver; and retina. Orthologous to human RBL1 (RB transcriptional corepressor like 1). [provided by Alliance of Genome Resources, Apr 2022]

Rbl1 Products(2)

mRNA Protein Name
NM_001139516.1 NP_001132988.1 retinoblastoma-like protein 1 isoform 2
NM_011249.2 NP_035379.2 retinoblastoma-like protein 1 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
7797074 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
7797074 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
15701640 MGI
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
10082561 MGI
part of transcription regulator complex IDA
IDA: Inferred from direct assay
10082561 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

retinoblastoma-like protein 1

107 kDa retinoblastoma-associated protein

retinoblastoma-like 1 (p107)

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-105024 FPL 62064 Inhibitor 99.25% Unkown
HY-N12231 Carbazomycin B Inhibitor / Unkown
HY-RS11729 RBL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rbl1 NCBI NCBI:5933