Reg1 - regenerating islet-derived 1 Gene

Also Known as PSP; PTP

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19692

Summary

Predicted to enable several functions, including growth factor activity; identical protein binding activity; and peptidoglycan binding activity. Involved in several processes, including pancreas regeneration; phosphatidylinositol 3-kinase signaling; and type B pancreatic cell differentiation. Acts upstream of or within with a positive effect on gene expression. Located in collagen-containing extracellular matrix. Is expressed in several structures, including esophagus; lung; and pancreas. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to several human genes including REG1A (regenerating family member 1 alpha). [provided by Alliance of Genome Resources, Apr 2022]

Reg1 Products (2)

mRNA Protein Name
NM_009042.2 NP_033068.1 lithostathine-1 precursor
NM_009042.2 NP_033068.1 lithostathine-1 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive effect gene expression IMP
IMP: Inferred from mutant phenotype
16405968 MGI
involved in pancreas regeneration IMP
IMP: Inferred from mutant phenotype
16405968 MGI
involved in phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: Inferred from mutant phenotype
16405968 MGI
involved in positive regulation of protein phosphorylation IMP
IMP: Inferred from mutant phenotype
16405968 MGI
involved in type B pancreatic cell differentiation IMP
IMP: Inferred from mutant phenotype
16405968 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lithostathine-1

  • REG 1

  • islet of Langerhans regenerating protein 1

  • pancreatic stone protein 1

  • pancreatic thread protein 1

  • regenerating protein 1

Recombinant Reg1 Proteins

Cat. No. Product Name Accession Purity
HY-P71462 Lithostathine-1/Reg1 Protein, Mouse (His-SUMO) P43137 (Q22-G165) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11818 REG1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-153836 Anivamersen Inhibitor / Unkown
HY-153836A Anivamersen sodium Inhibitor / Unkown
HY-RS11819 REG1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15986 ZC3H12A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24389 Reg1a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown