Dhrs3 - dehydrogenase/reductase (SDR family) member 3 Gene

Also Known as Rsdr1; retSDR1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20148

Summary

Enables NAD-retinol dehydrogenase activity. Acts upstream of or within several processes, including animal organ morphogenesis; negative regulation of retinoic acid receptor signaling pathway; and regulation of ossification. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in lipid droplet. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human DHRS3 (dehydrogenase/reductase 3). [provided by Alliance of Genome Resources, Apr 2022]

Dhrs3 Products (6)

mRNA Protein Name
NM_001172424.2 NP_001165895.1 short-chain dehydrogenase/reductase 3 isoform 2
NM_001357274.1 NP_001344203.1 short-chain dehydrogenase/reductase 3 isoform 2
NM_001357275.1 NP_001344204.1 short-chain dehydrogenase/reductase 3 isoform 3
NM_001357276.1 NP_001344205.1 short-chain dehydrogenase/reductase 3 isoform 3
NM_001357277.1 NP_001344206.1 short-chain dehydrogenase/reductase 3 isoform 4
NM_011303.7 NP_035433.1 short-chain dehydrogenase/reductase 3 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables all-trans-retinol dehydrogenase (NAD+) activity IMP
IMP: Inferred from mutant phenotype
24005908 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within bone morphogenesis IMP
IMP: Inferred from mutant phenotype
24005908 MGI
acts upstream of or within cardiac septum morphogenesis IMP
IMP: Inferred from mutant phenotype
24005908 MGI
acts upstream of or within negative regulation of retinoic acid receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
24005908 MGI
acts upstream of or within outflow tract morphogenesis IMP
IMP: Inferred from mutant phenotype
24005908 MGI
acts upstream of or within regulation of ossification IMP
IMP: Inferred from mutant phenotype
24005908 MGI
acts upstream of or within retinoid metabolic process IMP
IMP: Inferred from mutant phenotype
24005908 MGI
acts upstream of or within roof of mouth development IMP
IMP: Inferred from mutant phenotype
24005908 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

short-chain dehydrogenase/reductase 3

  • retinal short-chain dehydrogenase/reductase 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03741 DHRS3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20392 Dhrs3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26901 Dhrs3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dhrs3 NCBI NCBI:9249