Sez6 - seizure related gene 6 Gene

Also Known as sez-6; BSRP-C; D11Bhm177e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20370

Summary

Acts upstream of or within several processes, including excitatory postsynaptic potential; nervous system development; and regulation of dendrite development. Located in several cellular components, including dendrite; neuronal cell body; and perinuclear region of cytoplasm. Is expressed in several structures, including central nervous system; genitourinary system; liver; retina; and thymus. Orthologous to human SEZ6 (seizure related 6 homolog). [provided by Alliance of Genome Resources, Apr 2022]

Sez6 Products (2)

mRNA Protein Name
NM_001291225.1 NP_001278154.1 seizure protein 6 isoform 2 precursor
NM_021286.4 NP_067261.2 seizure protein 6 isoform 1 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within activation of protein kinase C activity IGI
IGI: Inferred from genetic interaction
16814779 MGI
acts upstream of or within adult locomotory behavior IGI
IGI: Inferred from genetic interaction
16814779 MGI
acts upstream of or within cerebellar Purkinje cell layer development IGI
IGI: Inferred from genetic interaction
16814779 MGI
acts upstream of or within excitatory postsynaptic potential IMP
IMP: Inferred from mutant phenotype
18031681 MGI
acts upstream of or within regulation of dendrite development IMP
IMP: Inferred from mutant phenotype
18031681 MGI
acts upstream of or within synapse maturation IGI
IGI: Inferred from genetic interaction
16814779 MGI
Cellular Component GO Annotation Evidence References Source
located in apical dendrite IDA
IDA: Inferred from direct assay
18031681 MGI
located in dendritic shaft IDA
IDA: Inferred from direct assay
18031681 MGI
located in dendritic spine IDA
IDA: Inferred from direct assay
18031681 MGI
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
16814779 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
16814779 MGI
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
19662096 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

seizure protein 6

  • brain-specific receptor-like protein C

Recombinant Sez6 Proteins

Cat. No. Product Name Accession Purity
HY-P78037 SEZ6/BSRP-C Protein, Mouse (HEK293, His) Q7TSK2 (L20-H922) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-170554 ABBV-706 Inhibitor 99.71% Phase 3

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12753 SEZ6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12754 SEZ6L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12755 SEZ6L2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18260 Sez6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18545 Sez6l Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19527 Sez6l2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24739 Sez6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25027 Sez6l Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26022 Sez6l2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991041 Turmetabart 99.75% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sez6 NCBI NCBI:124925