SEZ6/BSRP-C Protein, Mouse (HEK293, His)

The SEZ6/BSRP-C protein contributes significantly to cell-to-cell recognition and neuronal membrane signaling, playing a crucial role in fundamental processes of neural networks.SEZ6/BSRP-C is particularly important in balancing dendritic elongation and branching, which shapes the complex structure of neurons.SEZ6/BSRP-C Protein, Mouse (HEK293, His) is the recombinant mouse-derived SEZ6/BSRP-C protein, expressed by HEK293 , with C-His labeled tag.

The SEZ6/BSRP-C protein appears to have a significant role in cell-cell recognition and neuronal membrane signaling, suggesting its involvement in fundamental processes within neural networks. It seems to be particularly crucial in achieving a balance between dendrite elongation and branching during the intricate process of developing a complex dendritic arbor. The participation of SEZ6/BSRP-C in these events indicates its importance in shaping the structural intricacies of neurons. Moreover, its involvement in the development of appropriate excitatory synaptic connectivity highlights its potential role in establishing functional connections within neural circuits. Further exploration into the specific mechanisms underlying SEZ6/BSRP-C's influence on cell-cell recognition and dendritic arborization could provide valuable insights into its broader role in neural development and signaling.

Immobilized Mouse SEZ6, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Anti-SEZ6 Antibody, hFc Tag with the EC₅₀ of ≤10.2ng/ml determined by ELISA.

Mouse

HEK293

C-8*His

Q7TSK2 (L20-H922)

20370  [NCBI]

Extracellular Domain

LSSEAPITGEGHATGIRETDGELTAAPTPEQSDRGVHFVTTAPTLKLLNHHPLLEEFLQEGLEREEAPQPALPFQPDSPTHFTPSPLPRLTNQDNRPVFTSPTPAVAAAPTQPHSREKPWNLESKPPELSITSSLPPGPSMAVPTLLPEDRPSTTPPSQAWTPTQEGPGDMDRPWVPEVMSKTTGLGVEGTIATSTASGDDEETTTTIITTTVTTVQPPGPCSWNFSGPEGSLDSPTAPSSPSDVGLDCFYYISVYPGYGVEIKVENISLQEGETITVEGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPLPAGPGTFHFRYQAYLLSCHFPRRPAYGDVTVTSLHPGGSAHFHCATGYQLKGARFLTCLNATQPFWDSQEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPESQRLHLHFEKVSLAEDDDRLIIRNGNNVEAPPVYDSYEVEYLPIEGLLSSGRHFFVEFSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSAPSYPVGTTVEFSCDPGYTLEQGSIIIECVDLHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGSGDVLTFYDGDDLTARVLGQYSGPRGHFKLFTSMADVTIQFQSDPGTSALGYQQGFVIHFFEVPRNDTCPELPEIPNGWKNPSQPELVHGTVVTYQCYPGYQVVGSSILMCQWDLSWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYVCDQGFVLTGSAILTCHDRQAGSPKWSDRAPKCLLEQFKPCHGLSAPENGARSPEKRLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASLDGFYNGRSLDVAKAPAASSALDAAH

Approximately 145-150 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.

≥ 95%, as determined by Bis-Tris PAGE.

Lyophilized powder

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.