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SEZ6/BSRP-C Protein, Mouse (HEK293, His)

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The SEZ6/BSRP-C protein contributes significantly to cell-to-cell recognition and neuronal membrane signaling, playing a crucial role in fundamental processes of neural networks.SEZ6/BSRP-C is particularly important in balancing dendritic elongation and branching, which shapes the complex structure of neurons.SEZ6/BSRP-C Protein, Mouse (HEK293, His) is the recombinant mouse-derived SEZ6/BSRP-C protein, expressed by HEK293 , with C-His labeled tag.

For research use only. We do not sell to patients.
  • Species: Mouse
  • Source: HEK293
  • Storage:
    Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
  • SEZ6/BSRP-C Protein, Mouse (HEK293, His) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Technical Parameters
  • Product Properties
  • Documentation
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Biological Activity

Description

The SEZ6/BSRP-C protein contributes significantly to cell-to-cell recognition and neuronal membrane signaling, playing a crucial role in fundamental processes of neural networks.SEZ6/BSRP-C is particularly important in balancing dendritic elongation and branching, which shapes the complex structure of neurons.SEZ6/BSRP-C Protein, Mouse (HEK293, His) is the recombinant mouse-derived SEZ6/BSRP-C protein, expressed by HEK293 , with C-His labeled tag.

Background

The SEZ6/BSRP-C protein appears to have a significant role in cell-cell recognition and neuronal membrane signaling, suggesting its involvement in fundamental processes within neural networks. It seems to be particularly crucial in achieving a balance between dendrite elongation and branching during the intricate process of developing a complex dendritic arbor. The participation of SEZ6/BSRP-C in these events indicates its importance in shaping the structural intricacies of neurons. Moreover, its involvement in the development of appropriate excitatory synaptic connectivity highlights its potential role in establishing functional connections within neural circuits. Further exploration into the specific mechanisms underlying SEZ6/BSRP-C's influence on cell-cell recognition and dendritic arborization could provide valuable insights into its broader role in neural development and signaling.

Verified Bioactivity

Immobilized Mouse SEZ6, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Anti-SEZ6 Antibody, hFc Tag with the EC50 of ≤10.2ng/ml determined by ELISA.

Technical Parameters

  • Species Mouse
  • Source HEK293
  • Tag C-8*His
  • Accession

    Q7TSK2 (L20-H922)

  • Gene ID
    20370  [NCBI]
  • Molecular Construction
    • N-term
    • SEZ6 (L20-H922)
      Accession # Q7TSK2
    • 8*His
    • C-term
  • Protein Length

    Extracellular Domain

  • Synonyms

    SEZ6; HSEZ-6; Seizure Related 6 Homolog; BSRPC; Seizure Protein 6 Homolog; SEZ-6; Seizure Related 6 Homolog (Mouse)

  • AA Sequence

    LSSEAPITGEGHATGIRETDGELTAAPTPEQSDRGVHFVTTAPTLKLLNHHPLLEEFLQEGLEREEAPQPALPFQPDSPTHFTPSPLPRLTNQDNRPVFTSPTPAVAAAPTQPHSREKPWNLESKPPELSITSSLPPGPSMAVPTLLPEDRPSTTPPSQAWTPTQEGPGDMDRPWVPEVMSKTTGLGVEGTIATSTASGDDEETTTTIITTTVTTVQPPGPCSWNFSGPEGSLDSPTAPSSPSDVGLDCFYYISVYPGYGVEIKVENISLQEGETITVEGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPLPAGPGTFHFRYQAYLLSCHFPRRPAYGDVTVTSLHPGGSAHFHCATGYQLKGARFLTCLNATQPFWDSQEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPESQRLHLHFEKVSLAEDDDRLIIRNGNNVEAPPVYDSYEVEYLPIEGLLSSGRHFFVEFSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSAPSYPVGTTVEFSCDPGYTLEQGSIIIECVDLHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGSGDVLTFYDGDDLTARVLGQYSGPRGHFKLFTSMADVTIQFQSDPGTSALGYQQGFVIHFFEVPRNDTCPELPEIPNGWKNPSQPELVHGTVVTYQCYPGYQVVGSSILMCQWDLSWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYVCDQGFVLTGSAILTCHDRQAGSPKWSDRAPKCLLEQFKPCHGLSAPENGARSPEKRLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASLDGFYNGRSLDVAKAPAASSALDAAH

  • Predicted Molecular Mass

    98.8 kDa

  • Molecular Weight

    Approximately 145-150 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

  • Glycosylation

    Yes

  • Purity

    ≥ 95%, as determined by Bis-Tris PAGE.

Product Properties

Appearance

Lyophilized powder

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

Storage & Stability

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Calculators

Reconstitution Calculator

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

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Dilution Calculator

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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The Specific Activity Calculator Equation
  • Specific Activity (Unit/mg)
  • Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) Specific Activity (Unit/mg)
Unit/mg
= 106 ÷
Biological Activity (ED50) Biological Activity (ED50)
106 ÷
ng/mL
MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • SEZ6/BSRP-C Protein, Mouse (HEK293, His) Product Image