Turmetabart
Based on 1 Customer Validation
Turmetabart (Anti-SEZ6 Antibody (SC17)) is a humanized anti-SEZ6 IgG1 monoclonal antibody. Anti-SEZ6 Antibody (SC17) can be used to synthesize antibody-drug conjugates (ADC) product, ABBV-011. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
For research use only. We do not sell to patients.
- Purity: 99.75%
- CAS No.: 2650574-80-2
- Molecular Weight:144.6 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Human IgG1 kappa
Human
ADC antibodies act as the navigation system of ADC drugs and are primarily responsible for delivering payloads to target cells.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Q53EL9
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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IgG1-kappa
ELISA, FACS, Functional assay
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Immobilized HuSEZ6-ECD(20-925)-His can bind Anti-SEZ6 Antibody (SC17). The EC50 for this effect is 12.34 ng/mL. -
Flow Cytometry analysis of Hela cells labelling SEZ6 (red) with Turmetabart (HY-P991041). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
Chemical Information
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CAS No. 2650574-80-2
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Appearance Liquid
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Molecular Weight 144.6 kDa
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Color Colorless to light yellow
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SMILES
[Turmetabart]
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Synonyms
Anti-SEZ6 Antibody (SC17); ABBV-011 antibody; ABBV-706 antibody
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (256 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)