St8sia2 - ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 Gene

Also Known as STX; Siat8b; ST8SiaII

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20450

Summary

Enables alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity. Predicted to be involved in several processes, including ganglioside biosynthetic process; glycoprotein metabolic process; and neuron projection extension. Located in early endosome and recycling endosome. Is expressed in several structures, including central nervous system; future brain; genitourinary system; gut; and retina. Orthologous to human ST8SIA2 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]

St8sia2 Products (1)

mRNA Protein Name
NM_009181.2 NP_033207.2 alpha-2,8-sialyltransferase 8B precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity IDA
IDA: Inferred from direct assay
7782326 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
20479255 MGI
Biological Process GO Annotation Evidence References Source
involved in sialylation IDA
IDA: Inferred from direct assay
7782326 MGI
involved in sialylation IMP
IMP: Inferred from mutant phenotype
27534376 MGI
Cellular Component GO Annotation Evidence References Source
located in early endosome IDA
IDA: Inferred from direct assay
23303939 MGI
located in recycling endosome IDA
IDA: Inferred from direct assay
23303939 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-2,8-sialyltransferase 8B

  • SIAT8-B

  • polysialic acid synthase

  • sialyltransferase 8 (alpha-2, 8-sialyltransferase) B

  • sialyltransferase 8B

  • sialyltransferase St8Sia II

  • sialyltransferase X

  • sialytransferase St8Sia II

St8sia2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
St8sia2 O35696 CADM1 Homo sapiens Q9BY67
Glycosylase Assay
20479255
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13857 ST8SIA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens St8sia2 NCBI NCBI:8128