Serpina1a - serine (or cysteine) peptidase inhibitor, clade A, member 1A Gene

Also Known as PI1; Aat2; Dom1; Aat-2; Spi1-1; Spi1-3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20700

Summary

Predicted to enable serine-type endopeptidase inhibitor activity. Acts upstream of or within protein N-linked glycosylation; response to cytokine; and response to peptide hormone. Located in extracellular region. Is expressed in gut; liver lobe; and renal calyx. [provided by Alliance of Genome Resources, Apr 2022]

Serpina1a Products (2)

mRNA Protein Name
NM_001252569.1 NP_001239498.1 alpha-1-antitrypsin 1-1 isoform 2
NM_009243.4 NP_033269.1 alpha-1-antitrypsin 1-1 isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11961105 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within protein N-linked glycosylation IDA
IDA: Inferred from direct assay
11961105 MGI
acts upstream of or within response to cytokine IDA
IDA: Inferred from direct assay
15795238 MGI
acts upstream of or within response to peptide hormone IDA
IDA: Inferred from direct assay
15795238 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular region IDA
IDA: Inferred from direct assay
11961105 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-1-antitrypsin 1-1

  • AAT

  • alpha-1 protease inhibitor 1

  • alpha-1-antiproteinase

  • alpha-1-antitrypsin 2

  • serine (or cysteine) proteinase inhibitor, clade A, member 1a

  • serine protease inhibitor 1-1

  • serine protease inhibitor A1a

  • serpin A1a

Recombinant Serpina1a Proteins

Cat. No. Product Name Accession Purity
HY-P70979 Serpin A1a Protein, Mouse (HEK293, His) AAH11040.1 (E25-K413) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS29511 Serpina1a Mouse Pre-designed siRNA Set A / Unkown