Pknox2 - Pbx/knotted 1 homeobox 2 Gene

Also Known as Prep2; D230005H23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 208076

Summary

Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; actin filament binding activity; and actin monomer binding activity. Acts upstream of or within regulation of transcription by RNA polymerase II. Located in cytoplasm; cytoskeleton; and nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human PKNOX2 (PBX/knotted 1 homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]

Pknox2 Products (2)

mRNA Protein Name
NM_001029838.2 NP_001025009.1 homeobox protein PKNOX2
NM_148950.3 NP_683752.2 homeobox protein PKNOX2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
12412021 MGI
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
16847320 MGI
enables actin filament binding IDA
IDA: Inferred from direct assay
15339927 MGI
enables actin monomer binding IDA
IDA: Inferred from direct assay
15339927 MGI
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
16847320 MGI
enables sequence-specific DNA binding IGI
IGI: Inferred from genetic interaction
17049510 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
17049510 MGI
Cellular Component GO Annotation Evidence References Source
located in actin cytoskeleton IDA
IDA: Inferred from direct assay
15339927 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
12412021 MGI
located in microtubule cytoskeleton IDA
IDA: Inferred from direct assay
15339927 MGI
located in nucleus IDA
IDA: Inferred from direct assay
15339927 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein PKNOX2

  • PBX/knotted homeobox 2

  • homeobox protein PREP-2

  • homeodomain containing transcription factor PREP2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10610 PKNOX2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pknox2 NCBI NCBI:63876