Il20rb - interleukin 20 receptor beta Gene

Also Known as Fndc6; Gm186; Il20R2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 213208

Summary

Enables interleukin-20 binding activity. Acts upstream of or within several processes, including negative regulation of T cell proliferation; negative regulation of type IV hypersensitivity; and regulation of cytokine production. Predicted to be integral component of plasma membrane. Is expressed in foregut; male reproductive gland or organ; metanephros; skin; and thymus. Orthologous to human IL20RB (interleukin 20 receptor subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Il20rb Products (1)

mRNA Protein Name
NM_001033543.3 NP_001028715.2 interleukin-20 receptor subunit beta precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables interleukin-20 binding IPI
IPI: Inferred from physical interaction
21844205 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within CD8-positive, alpha-beta T cell homeostasis IMP
IMP: Inferred from mutant phenotype
19124723 MGI
acts upstream of or within T cell homeostasis IMP
IMP: Inferred from mutant phenotype
19124723 MGI
acts upstream of T cell proliferation IMP
IMP: Inferred from mutant phenotype
19124723 MGI
acts upstream of or within homeostasis of number of cells within a tissue IMP
IMP: Inferred from mutant phenotype
19124723 MGI
acts upstream of or within immune response-inhibiting signal transduction IMP
IMP: Inferred from mutant phenotype
19124723 MGI
acts upstream of or within inflammatory response to antigenic stimulus IMP
IMP: Inferred from mutant phenotype
19124723 MGI
acts upstream of interleukin-10 production IMP
IMP: Inferred from mutant phenotype
19124723 MGI
acts upstream of interleukin-2 production IMP
IMP: Inferred from mutant phenotype
19124723 MGI
acts upstream of interleukin-4 production IMP
IMP: Inferred from mutant phenotype
19124723 MGI
acts upstream of or within negative regulation of T cell proliferation IMP
IMP: Inferred from mutant phenotype
19124723 MGI
acts upstream of or within negative regulation of interleukin-2 production IMP
IMP: Inferred from mutant phenotype
19124723 MGI
acts upstream of or within negative regulation of type II interferon production IMP
IMP: Inferred from mutant phenotype
19124723 MGI
acts upstream of or within negative regulation of type IV hypersensitivity IMP
IMP: Inferred from mutant phenotype
19124723 MGI
acts upstream of or within positive regulation of interleukin-10 production IMP
IMP: Inferred from mutant phenotype
19124723 MGI
acts upstream of or within positive regulation of interleukin-4 production IMP
IMP: Inferred from mutant phenotype
19124723 MGI
acts upstream of or within regulation of T cell activation IMP
IMP: Inferred from mutant phenotype
19124723 MGI
acts upstream of type II interferon production IMP
IMP: Inferred from mutant phenotype
19124723 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-20 receptor subunit beta

  • fibronectin type III domain containing 6

Recombinant Il20rb Proteins

Cat. No. Product Name Accession Purity
HY-P76429 IL-20R beta Protein, Mouse (HEK293, His) E9Q9A6/NP_001028715 (V27-S225) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06733 IL20RB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il20rb NCBI NCBI:53833