IL20RB - interleukin 20 receptor subunit beta Gene

Also Known as DIRS1; FNDC6; IL-20R2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 53833

About IL20RB

Cytogenetic location: 3q22.3 Genomic coordinates (GRCh38): 3:136,957,983-137,011,085 (from NCBI)

This gene has 5 transcripts (splice variants), 152 orthologues and 11 paralogues. Biased expression in skin (RPKM 54.3) and esophagus (RPKM 20.8).

Summary

IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20 (IL20; MIM 605619) (Blumberg et al., 2001 [PubMed 11163236]).[supplied by OMIM, Feb 2009]

IL20RB Products (1)

mRNA Protein Name
NM_144717.4 NP_653318.2 interleukin-20 receptor subunit beta precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22802649 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

IL20RB Protein Structure

Tissue_fac

Tissue_fac: Tissue factor (17 - 124)

Interfer-bind

Interfer-bind: Interferon-alpha/beta receptor, fibronectin type III (155 - 225)

  • 0
  • 100
  • 200
  • 311 a.a.
Protein Preferred Names Protein Names

interleukin-20 receptor subunit beta

  • IL-20 receptor subunit beta

IL20RB Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
IL20RB Q6UXL0 Q9NYY1-PRO_0000015381 Homo sapiens Q9NYY1-PRO_0000015381
SPR
22802649
Intra
IL20RB Q6UXL0 Q9UHD0-PRO_0000015379 Homo sapiens Q9UHD0-PRO_0000015379
SPR
22802649
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant IL20RB Proteins

Cat. No. Product Name Accession Purity
HY-P72561 IL-20R beta Protein, Human (HEK293, Fc) Q6UXL0-1 (D30-A230) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P76428 IL-20R beta Protein, Human (sf9, His) Q6UXL0-1 (D30-A230) ≥ 90%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Fungal Esophagitis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06733 IL20RB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus IL20RB MGD MGI:2143266
Rattus norvegicus IL20RB RGD RGD:1566151
Macaca mulatta IL20RB VGNC VGNC:73725
Felis catus IL20RB VGNC VGNC:67773
Bos taurus IL20RB VGNC VGNC:30140
Canis familiaris IL20RB VGNC VGNC:41966
Others IL20RB NCBI