Wnt9a - wingless-type MMTV integration site family, member 9A Gene

Also Known as Wnt14; wnt-14

Species: Mus musculus

Gene Type: protein coding
Gene ID: 216795

Summary

Predicted to enable cytokine activity and Frizzled binding activity. Acts upstream of or within several processes, including embryonic morphogenesis; negative regulation of chondrocyte differentiation; and positive regulation of smoothened signaling pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including brain; craniocervical region bone; limb; reproductive system; and urethra. Human ortholog(s) of this gene implicated in pancreatic Cancer. Orthologous to human WNT9A (Wnt family member 9A). [provided by Alliance of Genome Resources, Apr 2022]

Wnt9a Products (1)

mRNA Protein Name
NM_139298.2 NP_647459.1 protein Wnt-9a precursor
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19422823 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within anatomical structure development IGI
IGI: Inferred from genetic interaction
16818445 MGI
acts upstream of or within canonical Wnt signaling pathway IGI
IGI: Inferred from genetic interaction
16818445 MGI
acts upstream of cartilage development IDA
IDA: Inferred from direct assay
19047045 MGI
acts upstream of chondrocyte differentiation IGI
IGI: Inferred from genetic interaction
16818445 MGI
acts upstream of chondrocyte differentiation IMP
IMP: Inferred from mutant phenotype
16818445 MGI
acts upstream of or within embryonic forelimb morphogenesis IDA
IDA: Inferred from direct assay
15371327 MGI
acts upstream of or within embryonic skeletal system morphogenesis IMP
IMP: Inferred from mutant phenotype
16818445 MGI
acts upstream of epithelial cell differentiation IMP
IMP: Inferred from mutant phenotype
16818445 MGI
acts upstream of or within negative regulation of cartilage development IDA
IDA: Inferred from direct assay
19047045 MGI
acts upstream of or within negative regulation of chondrocyte differentiation IGI
IGI: Inferred from genetic interaction
16818445 MGI
acts upstream of or within negative regulation of chondrocyte differentiation IMP
IMP: Inferred from mutant phenotype
16818445 MGI
acts upstream of or within negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IDA
IDA: Inferred from direct assay
19422823 MGI
acts upstream of or within negative regulation of programmed cell death IDA
IDA: Inferred from direct assay
19422823 MGI
acts upstream of or within positive regulation of epithelial cell differentiation IMP
IMP: Inferred from mutant phenotype
16818445 MGI
acts upstream of or within positive regulation of smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
16818445 MGI
acts upstream of smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
16818445 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein Wnt-9a

  • wingless-type MMTV integration site 14

  • wingless-type MMTV integration site 9A

Orthologs Information

Species Symbol Source ID
Homo sapiens Wnt9a NCBI NCBI:7483