Dhx33 - DEAH (Asp-Glu-Ala-His) box polypeptide 33 Gene

Mus musculus

Also known as Ddx33; 3110057P17Rik; 9430096J02Rik

Gene ID: 216877 | Gene type: protein coding

About Dhx33

Summary

Enables DNA-binding transcription factor binding activity; double-stranded RNA binding activity; and rDNA binding activity. Involved in positive regulation of MAPK cascade; regulation of gene expression; and translational initiation. Located in nucleolus and nucleoplasm. Orthologous to human DHX33 (DEAH-box helicase 33). [provided by Alliance of Genome Resources, Apr 2022]

Dhx33 Products(1)

mRNA	Protein	Name
NM_178367.4	NP_848144.3	ATP-dependent RNA helicase DHX33

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA-binding transcription factor binding	IPI IPI: Inferred from physical interaction	21930779	MGI
enables double-stranded RNA binding	IDA IDA: Inferred from direct assay	24037184	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	24037184	MGI
enables rDNA binding	IDA IDA: Inferred from direct assay	21930779	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of MAPK cascade	IMP IMP: Inferred from mutant phenotype	24037184	MGI
involved in positive regulation of NF-kappaB transcription factor activity	IMP IMP: Inferred from mutant phenotype	24037184	MGI
involved in positive regulation of transcription by RNA polymerase I	IDA IDA: Inferred from direct assay	21930779	MGI
involved in positive regulation of type I interferon production	IMP IMP: Inferred from mutant phenotype	24037184	MGI
involved in translational initiation	IDA IDA: Inferred from direct assay	26100019	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleolus	IDA IDA: Inferred from direct assay	21930779	MGI
located in nucleoplasm	IDA IDA: Inferred from direct assay	21930779	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

ATP-dependent RNA helicase DHX33

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 33	DEAH box protein 33
putative ATP-dependent RNA helicase DHX33

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-156418	KY386		99.01%	Unkown
HY-RS03752	DHX33 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Dhx33	NCBI	NCBI:56919

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