Unc45b - unc-45 myosin chaperone B Gene

Also Known as Cmya4; Unc45; D230041A13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 217012

Summary

Enables HSP90 protein binding activity. Acts upstream of or within chaperone-mediated protein folding. Located in cytosol. Is expressed in soleus and testis. Human ortholog(s) of this gene implicated in cataract 43 and myofibrillar myopathy. Orthologous to human UNC45B (unc-45 Myosin chaperone B). [provided by Alliance of Genome Resources, Apr 2022]

Unc45b Products (1)

mRNA Protein Name
NM_178680.4 NP_848795.3 protein unc-45 homolog B

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables Hsp90 protein binding IDA
IDA: Inferred from direct assay
18326487 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within chaperone-mediated protein folding IDA
IDA: Inferred from direct assay
18326487 MGI
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
18478096 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein unc-45 homolog B

  • UNC-45B

  • cardiomyopathy associated 4

  • striated muscle UNC45

  • unc-45 homolog B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15469 UNC45B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Unc45b NCBI NCBI:146862