Dnajc27 - DnaJ heat shock protein family (Hsp40) member C27 Gene

Mus musculus

Also known as Rbj; Rabj; C330021A05Rik

Gene ID: 217378 | Gene type: protein coding

About Dnajc27

Summary

Enables GTPase activity. Involved in positive regulation of ERK1 and ERK2 cascade and regulation of MAPK export from nucleus. Located in nucleus. Orthologous to human DNAJC27 (DnaJ heat shock protein family (HSP40) member C27). [provided by Alliance of Genome Resources, Apr 2022]

Dnajc27 Products(1)

mRNA	Protein	Name
NM_153082.4	NP_694722.2	dnaJ homolog subfamily C member 27

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables GTPase activity	IDA IDA: Inferred from direct assay	24746703	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	24746703	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of ERK1 and ERK2 cascade	IDA IDA: Inferred from direct assay	24746703	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleus	IDA IDA: Inferred from direct assay	24746703	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

dnaJ homolog subfamily C member 27

DnaJ (Hsp40) homolog, subfamily C, member 27	Rab-related GTP-binding protein
rab and DnaJ domain containing	rab and DnaJ domain-containing protein

Dnajc27 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Dnajc27	Q8CFP6	Map2k1	Mus musculus	P31938	Pull Down	24746703

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03883	DNAJC27 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Dnajc27	NCBI	NCBI:51277

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