DNAJC27 - DnaJ heat shock protein family (Hsp40) member C27 Gene

Homo sapiens

Also known as RBJ; RabJS

Gene ID: 51277 | Gene type: protein coding

About DNAJC27

Cytogenetic location: 2p23.3 Genomic coordinates (GRCh38): 2:24,943,636-24,972,094 (from NCBI)

This gene has 7 transcripts (splice variants), 204 orthologues and 68 paralogues. Broad expression in testis (RPKM 15.3), brain (RPKM 3.5) and 22 other tissues.

Summary

Predicted to enable GTPase activity. Predicted to be involved in intracellular protein transport and positive regulation of MAPK cascade. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

DNAJC27 Products(2)

mRNA	Protein	Name
NM_001198559.1	NP_001185488.1	dnaJ homolog subfamily C member 27 isoform 2
NM_016544.3	NP_057628.1	dnaJ homolog subfamily C member 27 isoform 1

DNAJC27 Protein Structure

Ras

DnaJ

0
100
200
273 a.a.

Protein Preferred Names

Protein Names

dnaJ homolog subfamily C member 27

DnaJ (Hsp40) homolog, subfamily C, member 27

Related Diseases

Diseases

Alias

Eyelid Benign Neoplasm

Tumor Of The Eyelid	Eyelid Neoplasms
Eyelid Neoplasm

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03883	DNAJC27 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	DNAJC27	MGD	MGI:2443036
Rattus norvegicus	DNAJC27	RGD	RGD:1564414
Bos taurus	DNAJC27	VGNC	VGNC:59212
Macaca mulatta	DNAJC27	VGNC	VGNC:106148

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