DNAJC27 - DnaJ heat shock protein family (Hsp40) member C27 Gene

Also Known as RBJ; RabJS

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51277

About DNAJC27

Cytogenetic location: 2p23.3 Genomic coordinates (GRCh38): 2:24,943,636-24,972,094 (from NCBI)

This gene has 7 transcripts (splice variants), 204 orthologues and 68 paralogues. Broad expression in testis (RPKM 15.3), brain (RPKM 3.5) and 22 other tissues.

Summary

Predicted to enable GTPase activity. Predicted to be involved in intracellular protein transport and positive regulation of MAPK cascade. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

DNAJC27 Products (2)

mRNA Protein Name
NM_001198559.1 NP_001185488.1 dnaJ homolog subfamily C member 27 isoform 2
NM_016544.3 NP_057628.1 dnaJ homolog subfamily C member 27 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DNAJC27 Protein Structure

Ras

Ras: Ras family (18 - 179)

DnaJ

DnaJ: DnaJ domain (219 - 268)

  • 0
  • 100
  • 200
  • 273 a.a.
Protein Preferred Names Protein Names

dnaJ homolog subfamily C member 27

  • DnaJ (Hsp40) homolog, subfamily C, member 27

DNAJC27 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
DNAJC27 Q9NZQ0 TFCP2 Homo sapiens Q12800
Y2H Array
32296183
Intra
DNAJC27 Q9NZQ0 TFCP2 Homo sapiens Q12800
Y2H Prey Pooling
25416956
Intra
DNAJC27 Q9NZQ0 TFCP2 Homo sapiens Q12800
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Eyelid Benign Neoplasm

  • Tumor Of The Eyelid

  • Eyelid Neoplasms

  • Eyelid Neoplasm
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03883 DNAJC27 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus DNAJC27 MGD MGI:2443036
Rattus norvegicus DNAJC27 RGD RGD:1564414
Bos taurus DNAJC27 VGNC VGNC:59212
Macaca mulatta DNAJC27 VGNC VGNC:106148
Others DNAJC27 NCBI