Atp6v0a2 - ATPase, H+ transporting, lysosomal V0 subunit A2 Gene

Also Known as ISF; Tj6; J6B7; SHIF; Stv1; TJ6M; TJ6s; ATP6a2; Atp6n2; Atp6n1d; V-ATPase a2; 8430408C20Rik; V-ATPase 116 kDa

Species: Mus musculus

Gene Type: protein coding
Gene ID: 21871

Summary

This gene encodes a subunit of vacuolar ATPase, a multimeric enzyme that localizes to intracellular vesicles and to the plasma membrane of specialized cells. The encoded protein is a component of the V(0) domain, which functions in proton translocation across membranes. Function of this gene is important in fetal-specific immune suppression during pregnancy. [provided by RefSeq, May 2013]

Atp6v0a2 Products (1)

mRNA Protein Name
NM_011596.5 NP_035726.2 V-type proton ATPase 116 kDa subunit a 2

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16415858 MGI
Cellular Component GO Annotation Evidence References Source
located in acrosomal vesicle IDA
IDA: Inferred from direct assay
11872743 MGI
located in intracellular organelle IDA
IDA: Inferred from direct assay
12672822 MGI
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
19549681 MGI
part of proton-transporting V-type ATPase complex IDA
IDA: Inferred from direct assay
12963731 MGI
part of proton-transporting V-type ATPase, V0 domain IDA
IDA: Inferred from direct assay
11872743 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

V-type proton ATPase 116 kDa subunit a 2

  • ATPase, H+ transporting, lysosomal (vacuolar proton pump) non-catalytic accessory protein 2 (38kD)

  • ATPase, H+ transporting, lysosomal V0 subunit a

  • T-cell expressing clone j6

  • V-ATPase 116 kDa subunit a 2

  • V-ATPase 116 kDa subunit a2

  • V-type proton ATPas

Atp6v0a2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Atp6v0a2 P15920 Cyth2 Mus musculus P63034
Pull Down
16415858
Intra
Atp6v0a2 P15920 Cyth2 Mus musculus P63034
Y2H
16415858
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-117200 Necrostatin-7 Inhibitor 99.64% Unkown
HY-122650 PHY34 Inhibitor 98.43% Unkown
HY-RS01217 ATP6V0A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01222 ATP6V0D2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atp6v0a2 NCBI NCBI:23545