VSTM2A - V-set and transmembrane domain containing 2A Gene

Also Known as VSTM2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 222008

About VSTM2A

This gene has 8 transcripts (splice variants), 192 orthologues and 5 paralogues. Biased expression in brain (RPKM 3.8), prostate (RPKM 1.6) and 4 other tissues.

Summary

Predicted to enable identical protein binding activity. Involved in several processes, including positive regulation of brown fat cell differentiation; positive regulation of lipid storage; and positive regulation of white fat cell proliferation. Predicted to be located in extracellular region. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

VSTM2A Products (3)

mRNA Protein Name
NM_001301009.2 NP_001287938.1 V-set and transmembrane domain-containing protein 2A isoform 2 precursor
NM_001317843.2 NP_001304772.1 V-set and transmembrane domain-containing protein 2A isoform 3 precursor
NM_182546.4 NP_872352.2 V-set and transmembrane domain-containing protein 2A isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
33961781 GOA
Biological Process GO Annotation Evidence References Source
involved in positive regulation of brown fat cell differentiation IMP
IMP: Inferred from mutant phenotype
28052263 GOA
involved in positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
28052263 GOA
involved in positive regulation of lipid storage IMP
IMP: Inferred from mutant phenotype
28052263 GOA
involved in positive regulation of white fat cell proliferation IMP
IMP: Inferred from mutant phenotype
28052263 GOA
Cellular Component GO Annotation Evidence References Source
NOT located in nucleus IDA
IDA: Inferred from direct assay
28052263 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

VSTM2A Protein Structure

V-set

V-set: Immunoglobulin V-set domain (29 - 137)

  • 0
  • 100
  • 200
  • 236 a.a.
Protein Preferred Names Protein Names

V-set and transmembrane domain-containing protein 2A

  • V-set and transmembrane domain containing 2

VSTM2A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
VSTM2A Q8TAG5 ACAD8 Homo sapiens Q9UKU7
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant VSTM2A Proteins

Cat. No. Product Name Accession Purity
HY-P71429 VSTM2A Protein, Human ( E84K, HEK293, His) Q8TAG5-2 (S25-F244, E84K) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15714 VSTM2A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta VSTM2A VGNC VGNC:79720
Canis familiaris VSTM2A VGNC VGNC:48309
Rattus norvegicus VSTM2A RGD RGD:1596197
Bos taurus VSTM2A VGNC VGNC:36842
Mus musculus VSTM2A MGD MGI:2384826
Felis catus VSTM2A VGNC VGNC:66982
Others VSTM2A NCBI