Sun2 - Sad1 and UNC84 domain containing 2 Gene

Also Known as Unc84b; C030011B15; B230369L08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 223697

Summary

Enables identical protein binding activity. Involved in centrosome localization; nuclear migration; and positive regulation of cell migration. Located in chromosome, telomeric region; condensed nuclear chromosome; and nuclear inner membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; liver and biliary system; and skeletal muscle. Orthologous to human SUN2 (Sad1 and UNC84 domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Sun2 Products (3)

mRNA Protein Name
NM_001205345.1 NP_001192274.1 SUN domain-containing protein 2 isoform 1
NM_001205346.1 NP_001192275.1 SUN domain-containing protein 2 isoform 2
NM_194342.3 NP_919323.2 SUN domain-containing protein 2 isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
26688217 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16380439 MGI
Biological Process GO Annotation Evidence References Source
involved in centrosome localization IMP
IMP: Inferred from mutant phenotype
19874786 MGI
involved in nuclear migration along microfilament IMP
IMP: Inferred from mutant phenotype
20724637 MGI
involved in nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration IMP
IMP: Inferred from mutant phenotype
19874786 MGI
involved in positive regulation of cell migration IMP
IMP: Inferred from mutant phenotype
20724637 MGI
Cellular Component GO Annotation Evidence References Source
located in chromosome, telomeric region IDA
IDA: Inferred from direct assay
17452644 MGI
located in condensed nuclear chromosome IDA
IDA: Inferred from direct assay
17452644 MGI
located in nuclear envelope IDA
IDA: Inferred from direct assay
17452644 MGI
located in nuclear inner membrane IDA
IDA: Inferred from direct assay
19933576 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SUN domain-containing protein 2

  • protein unc-84 homolog B

  • sad1/unc-84 protein-like 2

Sun2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Sun2 Q8BJS4 Tmem201 Mus musculus A2A8U2-3
Anti Tag CoIP
22349700
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14030 SUN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sun2 NCBI NCBI:25777