2. Gene
  3. Plcl2 - phospholipase C-like 2 Gene

Plcl2 - phospholipase C-like 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Plce2; PLC-L2; PRIP-2; mKIAA1092

Gene ID: 224860 | Gene type: protein coding

About Plcl2

Summary

Predicted to enable GABA Receptor binding activity. Involved in negative regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including B cell activation; gamma-aminobutyric acid signaling pathway; and negative regulation of B cell receptor signaling pathway. Predicted to be located in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human PLCL2 (Phospholipase C like 2). [provided by Alliance of Genome Resources, Apr 2022]

Plcl2 Products(1)

mRNA Protein Name
NM_013880.3 NP_038908.2 inactive phospholipase C-like protein 2
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within B cell proliferation involved in immune response IMP
IMP: Inferred from mutant phenotype
14517301 MGI
acts upstream of or within B-1a B cell differentiation IMP
IMP: Inferred from mutant phenotype
14517301 MGI
acts upstream of or within gamma-aminobutyric acid signaling pathway IGI
IGI: Inferred from genetic interaction
16754670 MGI
acts upstream of or within negative regulation of B cell receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
14517301 MGI
involved in negative regulation of cold-induced thermogenesis IGI
IGI: Inferred from genetic interaction
26706316 MGI
acts upstream of or within positive regulation of receptor binding IGI
IGI: Inferred from genetic interaction
16754670 MGI
acts upstream of or within regulation of synaptic transmission, GABAergic IGI
IGI: Inferred from genetic interaction
16754670 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

inactive phospholipase C-like protein 2

PLC-L(2)

PLC-epsilon-2

phospholipase C, epsilon 2

phospholipase C-L2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10665 PLCL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plcl2 NCBI NCBI:23228